用深度学习判断智齿与下牙槽神经关系,支持临床决策。
Deep Learning-based Assessment of the Relation Between the Third Molar and Mandibular Canal on Panoramic Radiographs using Local, Centralized, and Federated Learning
- 比较本地、集中和联邦学习三种方式分类智齿与神经重叠
- 集中训练效果最好(AUC 0.831),联邦学习次之且更安全
- 联邦学习适合多中心合作,保护患者隐私
下颌第三磨牙靠近下牙槽神经会增加损伤风险,全景片常用于评估该关系。自动化识别重叠可辅助临床分诊,减少不必要的CBCT检查。本研究比较了本地学习(LL)、联邦学习(FL)和集中学习(CL)在八个独立标注者划分的裁剪全景片上的二分类性能。采用预训练ResNet-34,在每种范式下训练并使用客户端优化阈值评估,全局阈值测试性能。通过AUC、准确率等指标,结合训练动态、Grad-CAM可视化及服务器聚合信号进行分析。测试集上,CL表现最佳(AUC 0.831;准确率0.782),FL居中(AUC 0.757;准确率0.703),而LL跨客户端泛化差(AUC范围0.619–0.734,均值0.672)。训练曲线显示LL模型过拟合严重,Grad-CAM显示CL和FL注意力更集中于解剖结构。总体表明,集中训练性能最优,而联邦学习提供隐私保护的可行替代方案。
原文摘要 · Abstract (English)
Impaction of the mandibular third molar in proximity to the mandibular canal increases the risk of inferior alveolar nerve injury. Panoramic radiography is routinely used to assess this relationship. Automated classification of molar-canal overlap could support clinical triage and reduce unnecessary CBCT referrals, while federated learning (FL) enables multi-center collaboration without sharing patient data. We compared Local Learning (LL), FL, and Centralized Learning (CL) for binary overlap/no-overlap classification on cropped panoramic radiographs partitioned across eight independent labelers. A pretrained ResNet-34 was trained under each paradigm and evaluated using per-client metrics with locally optimized thresholds and pooled test performance with a global threshold. Performance was assessed using area under the receiver operating characteristic curve (AUC) and threshold-based metrics, alongside training dynamics, Grad-CAM visualizations, and server-side aggregate monitoring signals. On the test set, CL achieved the highest performance (AUC 0.831; accuracy = 0.782), FL showed intermediate performance (AUC 0.757; accuracy = 0.703), and LL generalized poorly across clients (AUC range = 0.619-0.734; mean = 0.672). Training curves suggested overfitting, particularly in LL models, and Grad-CAM indicated more anatomically focused attention in CL and FL. Overall, centralized training provided the strongest performance, while FL offers a privacy-preserving alternative that outperforms LL.
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