arXiv:2603.14120cs.CV2026-03

用欠采样数据提升低场MRI质量,还能评估模型在新数据上的表现。

Low-Field Magnetic Resonance Image Quality Enhancement using Undersampled k-Space and Out-of-Distribution Generalisation

  • 在k空间直接重建图像,同时处理实部虚部。
  • 在低场脑部MRI上达到高场全采样水平的图像质量。
  • 首次融合重建、增强与不确定性量化,适合医学影像研究者。

低场磁共振成像(MRI)虽具成本优势,但存在扫描时间长、图像质量差的问题。通过k空间欠采样可加速成像,但现有图像质量增强方法多依赖空间域后处理。深度学习虽在两域均达先进水平,但多数模型仅在分布内(InD)数据上训练评估,对分布外(OOD)数据的表现缺乏了解。为此,本文提出一种新框架:直接从欠采样低场MRI k空间重建出高场级图像,量化采样率影响,并在OOD数据上评估模型泛化能力。采用k空间双通道U-Net联合处理欠采样k空间的实部与虚部,恢复缺失频率信息;引入集成策略生成不确定性图。在低场脑部MRI数据集上的实验表明,该方法优于空间域及当前最优基线,在使用OOD数据时仍能达到全采样高场级图像质量。据我们所知,这是首个将低场图像重建、基于欠采样k空间的质量增强与不确定性量化统一于一个框架的工作。

原文摘要 · Abstract (English)

Low-field magnetic resonance imaging (MRI) offers affordable access to diagnostic imaging but faces challenges such as prolonged acquisition times and reduced image quality. Although accelerated imaging via k-space undersampling helps reduce scan time, image quality enhancement methods often rely on spatial-domain postprocessing. Deep learning achieved state-of-the-art results in both domains. However, most models are trained and evaluated using in-distribution (InD) data, creating a significant gap in understanding model performance when tested using out-of-distribution (OOD) data. To address these issues, we propose a novel framework that reconstructs high-field-like MR images directly from undersampled low-field MRI k-space, quantifies the impact of reduced sampling, and evaluates the generalisability of the model using OOD. Our approach utilises a k-space dual channel U-Net to jointly process the real and imaginary components of undersampled k-space, restoring missing frequency content, and incorporates an ensemble strategy to generate uncertainty maps. Experiments on low-field brain MRI demonstrate that our k-space-driven image quality enhancement outperforms the counterpart spatial-domain and other state-of-the-art baselines, achieving image quality comparable to full high-field k-space acquisitions using OOD data. To the best of our knowledge, this work is among the first to combine low-field MR image reconstruction, quality enhancement using undersampled k-space, and uncertainty quantification within a unified framework.

MRI重建k空间不确定性量化

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