arXiv:2603.18797cs.CV2026-03中稿 · ECCV被引 1

将血管类结构转化为可学习的隐向量,实现高效重建与生成。

VesselTok: Tokenizing Vessel-like 3D Biomedical Graph Representations for Reconstruction and Generation

  • 基于中心线点和伪半径编码管状结构,学习参数化隐表示
  • 在肺气道、肺血管、脑血管上均实现复杂拓扑的鲁棒编码
  • 支持未见解剖结构泛化、生成合理图形,适配下游逆问题

空间图为血管、气道和神经网络等弯曲解剖结构提供了轻量且优雅的表示方式。准确建模这些图对临床与生物医学研究至关重要。然而,大规模网络的高空间分辨率极大增加了复杂性,带来显著计算挑战。本文提出VesselTok框架,从参数化形状角度处理空间密集图,学习潜在表示(令牌)。VesselTok利用带伪半径的中心线点有效编码管状几何特征,通过条件于中心线点的新颖潜在表示,学习血管类管状结构的神经隐式表示。我们在多种解剖结构(包括肺气道、肺血管和脑血管)上验证了VesselTok性能,凸显其对复杂拓扑的鲁棒编码能力。为证明所学潜在表示的有效性,我们展示了其:(i) 可泛化至未见解剖结构,(ii) 支持生成合理解剖图的生成建模,(iii) 能有效迁移至下游逆问题如链接预测。

原文摘要 · Abstract (English)

Spatial graphs provide a lightweight and elegant representation of curvilinear anatomical structures such as blood vessels, lung airways, and neuronal networks. Accurately modeling these graphs is crucial in clinical and (bio-)medical research. However, the high spatial resolution of large networks drastically increases their complexity, resulting in significant computational challenges. In this work, we aim to tackle these challenges by proposing VesselTok, a framework that approaches spatially dense graphs from a parametric shape perspective to learn latent representations (tokens). VesselTok leverages centerline points with a pseudo radius to effectively encode tubular geometry. Specifically, we learn a novel latent representation conditioned on centerline points to encode neural implicit representations of vessel-like, tubular structures. We demonstrate VesselTok's performance across diverse anatomies, including lung airways, lung vessels, and brain vessels, highlighting its ability to robustly encode complex topologies. To prove the effectiveness of VesselTok's learnt latent representations, we show that they (i) generalize to unseen anatomies, (ii) support generative modeling of plausible anatomical graphs, and (iii) transfer effectively to downstream inverse problems, such as link prediction.

三维建模隐式表示生成模型医学图像

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