arXiv:2603.21095cs.CVcs.AI2026-03

用对抗正则化提升甲状腺超声多任务诊断一致性

Representation-Level Adversarial Regularization for Clinically Aligned Multitask Thyroid Ultrasound Assessment

  • 联合分割与TI-RADS分级,用辐射组学目标引导分类特征
  • 在公开数据集上风险分层准确率提升,分割质量不下降
  • 适合医学影像多任务建模,尤其关注临床一致性场景

甲状腺超声是评估结节并决定是否穿刺的首选检查。常规报告中,放射科医生需同时提供结节轮廓用于测量和基于超声标准的TI-RADS风险分级。然而,不同医生在轮廓勾画风格和风险评级上存在差异,导致监督信号不一致,影响模型训练效果。本文提出一种临床引导的多任务框架,通过单个模型联合预测结节掩码和TI-RADS类别。为使风险预测基于有意义的临床证据,训练时使用紧凑的TI-RADS对齐辐射组学目标引导分类嵌入,同时保留深层判别特征。针对标注者间变异导致的任务梯度竞争问题,引入代表层面对抗性梯度正则化(RLAR),通过潜空间中的对抗方向作为任务敏感性几何探针,惩罚任务间对抗方向过度对齐。在公开的TI-RADS数据集上,该方法相比单任务和传统多任务基线,在保持分割质量的同时持续提升风险分层性能。代码与预训练模型将公开。

原文摘要 · Abstract (English)

Thyroid ultrasound is the first-line exam for assessing thyroid nodules and determining whether biopsy is warranted. In routine reporting, radiologists produce two coupled outputs: a nodule contour for measurement and a TI-RADS risk category based on sonographic criteria. Yet both contouring style and risk grading vary across readers, creating inconsistent supervision that can degrade standard learning pipelines. In this paper, we address this workflow with a clinically guided multitask framework that jointly predicts the nodule mask and TI-RADS category within a single model. To ground risk prediction in clinically meaningful evidence, we guide the classification embedding using a compact TI-RADS aligned radiomics target during training, while preserving complementary deep features for discriminative performance. However, under annotator variability, naive multitask optimization often fails not because the tasks are unrelated, but because their gradients compete within the shared representation. To make this competition explicit and controllable, we introduce RLAR, a representation-level adversarial gradient regularizer. Rather than performing parameter-level gradient surgery, RLAR uses each task's normalized adversarial direction in latent space as a geometric probe of task sensitivity and penalizes excessive angular alignment between task-specific adversarial directions. On a public TI-RADS dataset, our clinically guided multitask model with RLAR consistently improves risk stratification while maintaining segmentation quality compared to single-task training and conventional multitask baselines. Code and pretrained models will be released.

医学影像多任务学习对抗正则甲状腺超声

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