arXiv:2603.23694cs.CV2026-03

将对比学习融入注册模型,提升医学影像对齐精度。

CoRe: Joint Optimization with Contrastive Learning for Medical Image Registration

  • 直接在注册框架中联合优化对比学习与配准目标。
  • 在腹腔和胸腔影像上优于现有强基线方法。
  • 适合需要高精度配准的医学影像分析场景。

医学图像配准是医学图像分析中的基础任务,用于对齐不同模态或时间点的图像。然而,强度不一致和非线性组织形变给配准方法的鲁棒性带来挑战。近期基于自监督表征学习的方法通过预训练特征提取器生成鲁棒的解剖嵌入,进而用于配准,展现出良好前景。本文提出一种新框架,将等变对比学习直接集成到注册模型中。该方法利用对比学习学习对组织形变不变的鲁棒特征表示,并通过联合优化对比学习与注册目标,确保所学表征既具信息量又适用于注册任务。我们在腹部和胸腔图像注册任务上进行评估,涵盖同患者与异患者场景。实验结果表明,将对比学习直接融入注册框架能显著提升性能,超越多个强基线方法。

原文摘要 · Abstract (English)

Medical image registration is a fundamental task in medical image analysis, enabling the alignment of images from different modalities or time points. However, intensity inconsistencies and nonlinear tissue deformations pose significant challenges to the robustness of registration methods. Recent approaches leveraging self-supervised representation learning show promise by pre-training feature extractors to generate robust anatomical embeddings, that farther used for the registration. In this work, we propose a novel framework that integrates equivariant contrastive learning directly into the registration model. Our approach leverages the power of contrastive learning to learn robust feature representations that are invariant to tissue deformations. By jointly optimizing the contrastive and registration objectives, we ensure that the learned representations are not only informative but also suitable for the registration task. We evaluate our method on abdominal and thoracic image registration tasks, including both intra-patient and inter-patient scenarios. Experimental results demonstrate that the integration of contrastive learning directly into the registration framework significantly improves performance, surpassing strong baseline methods.

医学影像图像配准对比学习

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