用步态分析预测衰老脆弱性,实现无创、可扩展的临床评估。
The Gait Signature of Frailty: Transfer Learning based Deep Gait Models for Scalable Frailty Assessment
- 基于预训练步态模型迁移学习,适应小样本脆弱性分类任务。
- 冻结低层特征、允许高层自适应,提升模型稳定性和泛化能力。
- 关注下肢与骨盆区域,结果与生物力学理论一致,适合临床应用。
脆弱性是老年医学中生理储备下降、对压力易感性增加的综合征。但当前脆弱性评估主观性强、标准不一且难以规模化。步态作为生物老化的敏感指标,能提前捕捉多系统衰退。然而,现有计算机视觉在步态脆弱性评估中的应用受限于小规模、不平衡的数据集及缺乏临床代表性基准。本文构建了一个公开的、基于轮廓的步态数据集,覆盖完整脆弱性谱系,包含使用助行器的老年人群。基于此数据集,我们评估了预训练步态识别模型在有限数据下的迁移学习效果。研究对比了卷积与混合注意力架构,发现预测性能主要取决于表示迁移策略而非模型复杂度。选择性冻结低层步态特征而允许高层特征自适应,优于全微调或严格冻结。保守处理类别不平衡进一步提升训练稳定性,结合互补学习目标可增强对相邻脆弱状态的区分能力。可解释性分析显示模型持续关注下肢和骨盆区域,与已知脆弱性生物力学关联一致。研究证明步态表征学习是一种可扩展、非侵入式且可解释的脆弱性评估框架,支持现代生物特征建模融入老龄化研究与临床实践。
原文摘要 · Abstract (English)
Frailty is a condition in aging medicine characterized by diminished physiological reserve and increased vulnerability to stressors. However, frailty assessment remains subjective, heterogeneous, and difficult to scale in clinical practice. Gait is a sensitive marker of biological aging, capturing multisystem decline before overt disability. Yet the application of modern computer vision to gait-based frailty assessment has been limited by small, imbalanced datasets and a lack of clinically representative benchmarks. In this work, we introduce a publicly available silhouette-based frailty gait dataset collected in a clinically realistic setting, spanning the full frailty spectrum and including older adults who use walking aids. Using this dataset, we evaluate how pretrained gait recognition models can be adapted for frailty classification under limited data conditions. We study both convolutional and hybrid attention-based architectures and show that predictive performance depends primarily on how pretrained representations are transferred rather than architectural complexity alone. Across models, selectively freezing low-level gait representations while allowing higher-level features to adapt yields more stable and generalizable performance than either full fine-tuning or rigid freezing. Conservative handling of class imbalance further improves training stability, and combining complementary learning objectives enhances discrimination between clinically adjacent frailty states. Interpretability analyses reveal consistent model attention to lower-limb and pelvic regions, aligning with established biomechanical correlates of frailty. Together, these findings establish gait-based representation learning as a scalable, non-invasive, and interpretable framework for frailty assessment and support the integration of modern biometric modeling approaches into aging research and clinical practice.
Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。