用平板数据建模儿童认知运动发展轨迹,早筛潜在发育问题
Longitudinal Digital Phenotyping for Early Cognitive-Motor Screening
- 基于多年平板交互数据,用无监督学习识别三种发育类型
- 低表现组超90%早期稳定,提示早期缺陷易持续
- 适合关注儿童发育监测与个性化干预的临床研究者
早期发现异常的认知运动发育对及时干预至关重要,但传统评估依赖主观且静态的判断。数字设备的融合为通过数字生物标志物实现连续、客观监测提供了可能。本文提出一种基于人工智能的纵向框架,用于建模18个月至8岁儿童的发展轨迹。基于多年学术周期内收集的平板交互数据,分析了六项认知运动任务(如精细运动控制、反应时间)。采用降维(t-SNE)和无监督聚类(K-Means++)识别出三种显著不同的发育表型,并追踪个体在各表型间的转变。分析显示存在低、中、高三个表现群组。关键发现是:低表现群组在早期阶段具有极高稳定性(保留率>90%),表明早期缺陷往往持续存在而无干预;高表现群组则表现出更大变异性,可能反映参与度差异。本研究验证了在触屏数据上使用无监督学习揭示异质性发育路径的有效性。所识别的表型可作为可扩展、数据驱动的认知成长代理指标,为早期筛查工具和个性化儿科干预提供基础。
原文摘要 · Abstract (English)
Early detection of atypical cognitive-motor development is critical for timely intervention, yet traditional assessments rely heavily on subjective, static evaluations. The integration of digital devices offers an opportunity for continuous, objective monitoring through digital biomarkers. In this work, we propose an AI-driven longitudinal framework to model developmental trajectories in children aged 18 months to 8 years. Using a dataset of tablet-based interactions collected over multiple academic years, we analyzed six cognitive-motor tasks (e.g., fine motor control, reaction time). We applied dimensionality reduction (t-SNE) and unsupervised clustering (K-Means++) to identify distinct developmental phenotypes and tracked individual transitions between these profiles over time. Our analysis reveals three distinct profiles: low, medium, and high performance. Crucially, longitudinal tracking highlights a high stability in the low-performance cluster (>90% retention in early years), suggesting that early deficits tend to persist without intervention. Conversely, higher-performance clusters show greater variability, potentially reflecting engagement factors. This study validates the use of unsupervised learning on touchscreen data to uncover heterogeneous developmental paths. The identified profiles serve as scalable, data-driven proxies for cognitive growth, offering a foundation for early screening tools and personalized pediatric interventions.
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