arXiv:2603.28560cs.CV2026-03被引 1

用渐进式训练提升心肌瘢痕分割精度,尤其适合模糊或微量瘢痕。

Curriculum-Guided Myocardial Scar Segmentation for Ischemic and Non-ischemic Cardiomyopathy

  • 按信心高低顺序训练模型,从清晰瘢痕逐步过渡到模糊区域。
  • 在微量和弥散性瘢痕上分割准确率显著优于传统方法。
  • 适合临床中标签不一致、图像质量差的复杂病例分析。

心肌瘢痕的识别与量化对心血管疾病诊疗至关重要。然而,由于患者间对比增强差异、造影剂清除后成像条件不佳,以及弥漫性瘢痕标注因观察者差异导致的不一致性,从延迟钆增强心脏磁共振(LGE-CMR)图像中可靠分割瘢痕仍具挑战。本文提出一种基于课程学习的框架,通过渐进式训练策略,引导模型先学习高置信度、边界清晰的瘢痕区域,再逐步处理低置信度或视觉模糊的样本(尤其是瘢痕负荷较低者)。该方法使网络具备更强的鲁棒性,能有效应对不确定标签和细微瘢痕特征,这些在常规训练中常被忽略。实验表明,该方法在微量及弥散性瘢痕分割任务中显著提升准确性与一致性,优于标准训练基线。该策略为利用不完美数据提升临床心肌瘢痕定量能力提供了可解释的路径。代码已开源。

原文摘要 · Abstract (English)

Identification and quantification of myocardial scar is important for diagnosis and prognosis of cardiovascular diseases. However, reliable scar segmentation from Late Gadolinium Enhancement Cardiac Magnetic Resonance (LGE-CMR) images remains a challenge due to variations in contrast enhancement across patients, suboptimal imaging conditions such as post contrast washout, and inconsistencies in ground truth annotations on diffuse scars caused by inter observer variability. In this work, we propose a curriculum learning-based framework designed to improve segmentation performance under these challenging conditions. The method introduces a progressive training strategy that guides the model from high-confidence, clearly defined scar regions to low confidence or visually ambiguous samples with limited scar burden. By structuring the learning process in this manner, the network develops robustness to uncertain labels and subtle scar appearances that are often underrepresented in conventional training pipelines. Experimental results show that the proposed approach enhances segmentation accuracy and consistency, particularly for cases with minimal or diffuse scar, outperforming standard training baselines. This strategy provides a principled way to leverage imperfect data for improved myocardial scar quantification in clinical applications. Our code is publicly available on GitHub.

心肌瘢痕医学图像课程学习分割

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