arXiv:2604.07361cs.LG2026-04

用大模型增强脑图神经网络,提升功能磁共振分析性能

BLEG: LLM Functions as Powerful fMRI Graph-Enhancer for Brain Network Analysis

  • 用大模型生成脑图数据的文本增强表示,降低特征稀疏性
  • 通过联合训练与适配器微调,使图神经网络在多个数据集上表现更优
  • 无需全量微调大模型,适合资源有限的研究者快速应用

图神经网络(GNN)广泛应用于基于预处理功能磁共振成像(fMRI)数据的脑网络分析任务,但受限于高维特征稀疏性和单一模态神经图谱中领域知识的不足。大语言模型(LLMs)具备强大的表征能力,将它们与图模型结合是潜在突破方向。尽管多模态大模型已进入神经科学领域,但其与图结构数据的融合仍处于空白。本文提出BLEG方法,分三阶段实现:首先通过提示工程获取增强的文本描述;其次设计低代价的LLM-LM指令微调策略,生成优化文本表示;再与GNN协同训练进行粗粒度对齐;最后针对下游任务微调适配器。引入语言模型与GNN输出之间的对齐损失,进一步强化图神经网络表征。在多个数据集上的大量实验验证了该方法的优越性。代码已开源。

原文摘要 · Abstract (English)

Graph Neural Networks (GNNs) have been widely used in diverse brain network analysis tasks based on preprocessed functional magnetic resonance imaging (fMRI) data. However, their performances are constrained due to high feature sparsity and inherent limitations of domain knowledge within uni-modal neurographs. Meanwhile, large language models (LLMs) have demonstrated powerful representation capabilities. Combining LLMs with GNNs presents a promising direction for brain network analysis. While LLMs and MLLMs have emerged in neuroscience, integration of LLMs with graph-based data remains unexplored. In this work, we deal with these issues by incorporating LLM's powerful representation and generalization capabilities. Considering great cost for directly tuning LLMs, we instead function LLM as enhancer to boost GNN's performance on downstream tasks. Our method, namely BLEG, can be divided into three stages. We firstly prompt LLM to get augmented texts for fMRI graph data, then we design a LLM-LM instruction tuning method to get enhanced textual representations at a relatively lower cost. GNN is trained together for coarsened alignment. Finally we finetune an adapter after GNN for given downstream tasks. Alignment loss between LM and GNN logits is designed to further enhance GNN's representation. Extensive experiments on different datasets confirmed BLEG's superiority.Code can be available at https://github.com/KamonRiderDR/BLEG.

脑网络分析大模型增强图神经网络fMRI

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