arXiv:2604.07424cs.AIcs.CY2026-04

分析5.8万项NIH资助项目,揭示AI在生物医学研究中的分布与应用差距

An Analysis of Artificial Intelligence Adoption in NIH-Funded Research

  • 用大模型结合人工校验,自动分类和总结海量科研项目
  • AI占NIH项目15.9%,但仅14.7%进入临床应用,79%仍处研发阶段
  • 健康不平等问题仅占AI资助的5.7%,与使命严重脱节

理解人工智能(AI)与机器学习(ML)在国立卫生研究院(NIH)资助项目中的采用情况,对科研资助策略、机构规划和卫生政策至关重要。大语言模型(LLMs)的出现彻底改变了研究景观分析方式,使研究人员能够从数千份非结构化研究文档中进行大规模语义提取。本文展示了一种人机协作的研究方法,利用LLMs实现对科研描述的大规模自动分类与摘要。基于该方法,我们对2025年58,746项NIH资助的生物医学研究项目进行了全面分析。结果显示:(1) AI占NIH项目组合的15.9%,享有13.4%的经费溢价,主要集中在疾病领域的发现、预测与数据整合;(2) 存在显著的研究到部署差距,79%的AI项目仍处于研发阶段,仅有14.7%进入临床部署或实施;(3) 健康不平等研究仅占AI资助工作的5.7%,与其在NIH使命中的重要性严重不符。这些发现为制定以证据为基础的政策干预措施提供了框架,以推动NIH的AI项目更契合健康公平目标与战略研究优先事项。

原文摘要 · Abstract (English)

Understanding the landscape of artificial intelligence (AI) and machine learning (ML) adoption across the National Institutes of Health (NIH) portfolio is critical for research funding strategy, institutional planning, and health policy. The advent of large language models (LLMs) has fundamentally transformed research landscape analysis, enabling researchers to perform large-scale semantic extraction from thousands of unstructured research documents. In this paper, we illustrate a human-in-the-loop research methodology for LLMs to automatically classify and summarize research descriptions at scale. Using our methodology, we present a comprehensive analysis of 58,746 NIH-funded biomedical research projects from 2025. We show that: (1) AI constitutes 15.9% of the NIH portfolio with a 13.4% funding premium, concentrated in discovery, prediction, and data integration across disease domains; (2) a critical research-to-deployment gap exists, with 79% of AI projects remaining in research/development stages while only 14.7% engage in clinical deployment or implementation; and (3) health disparities research is severely underrepresented at just 5.7% of AI-funded work despite its importance to NIH's equity mission. These findings establish a framework for evidence-based policy interventions to align the NIH AI portfolio with health equity goals and strategic research priorities.

AI应用健康公平科研资助大模型

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