AI医疗助手会因身份不同拒绝患者必要治疗,暴露安全训练的潜在危害。
IatroBench: Pre-Registered Evidence of Iatrogenic Harm from AI Safety Measures
- 通过60个预注册临床场景测试,发现模型对患者与医生的回应差异达0.38分
- 最安全训练的模型Opus对患者拒绝率比医生高13.1分,且抑制已知知识
- 现有评估工具无法识别隐瞒性错误,导致危害被系统性忽视
在六种前沿模型(共3600次响应)和六十个预注册临床情景中,研究测量了因身份不同导致的医疗失误。即使临床事实完全相同,当请求者为患者时,高度安全训练的模型会拒绝提供苯二氮䓬类药物的完整减量方案,而对医生则提供。该现象称为身份依赖性隐瞒:五种可测试模型均对医生更支持(决策差距+0.38,p=0.003),患者成功率下降13.1分(p<0.0001)。最极端出现在安全强化最强的Opus模型,差距达+0.65。触发因素并非专业资质,而是缺乏专业或认知信号——律师或知情普通民众可恢复被拒建议。仅评估错误行为的基准会误判三类机制。Opus在医生提问下压制其已知知识;Llama 4在两种身份下均表现不佳;GPT-5.2的过滤器剔除33.2%医生回应但不删减普通人回应。评估流程复刻了训练层的盲点:标准大模型裁判在81.5%本应标记为有害的回应中未识别出遗漏伤害(kappa=0.066)。这些情景专为制造冲突设计,其发生率反映实验设计,不代表真实世界普遍性。
原文摘要 · Abstract (English)
A heavily safety-trained model will hand a physician the full, patient-followable benzodiazepine taper and refuse it to the patient who needs it, over identical clinical facts; the knowledge is present either way. IatroBench measures that asymmetry across sixty pre-registered clinical scenarios and six frontier models (3,600 responses), scoring each on two axes, commission harm (what a response gets wrong) and omission harm (what it withholds), through a physician-authored structured evaluation validated by a second physician (weighted kappa 0.571, within-1 agreement 96%). Holding clinical content fixed and varying only whether the asker presents as patient or physician yields what we call identity-contingent withholding: all five testable models give the physician more (a decoupling gap of +0.38, p = 0.003; a 13.1-point fall in layperson hit rates on safety-colliding actions, p < 0.0001; no change on the rest), and the gap runs widest in the most heavily safety-trained model, Opus (+0.65). The trigger is the absence of any professional or epistemic signal rather than a credential, since a lawyer or an informed layperson recovers what the patient is refused. A commission-only benchmark would score three mechanisms alike. Opus suppresses what physician framing proves it knows; Llama 4 is incompetent in either framing; GPT-5.2's filter strips 33.2% of its physician responses and none of the lay ones. The evaluation layer inherits the blindness of the training layer; a standard LLM judge scores zero omission harm on 81.5% of the responses our pipeline flags harmful (kappa 0.066), so the instrument built to detect the failure reproduces it. The scenarios are engineered for collision; their rates describe that design and say nothing about ordinary prevalence.
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