提出基于编码单元的细粒度视频加密方法，精准保护敏感区域。

ROI (Region of Interest) video selective encryption based on H.265/HEVC is a technology that protects the sensitive regions of videos by perturbing the syntax elements associated with target areas. However, existing methods typically adopt Tile (with a relatively large size) as the minimum encryption unit, which suffers from problems such as inaccurate encryption regions and low encryption precision. This low-precision encryption makes them difficult to apply in sensitive fields such as medicine, military, and remote sensing. In order to address the aforementioned problem, this paper proposes a fine-grained ROI video selective encryption algorithm based on Coding Units (CUs) and prompt segmentation. First, to achieve a more precise ROI acquisition, we present a novel ROI mapping approach based on prompt segmentation. This approach enables precise mapping of ROIs to small $8\times8$ CU levels, significantly enhancing the precision of encrypted regions. Second, we propose a selective encryption scheme based on multiple syntax elements, which distorts syntax elements within high-precision ROI to effectively safeguard ROI security. Finally, we design a diffusion isolation based on Pulse Code Modulation (PCM) mode and MV restriction, applying PCM mode and MV restriction strategy to the affected CU to address encryption diffusion during prediction. The above three strategies break the inherent mechanism of using Tiles in existing ROI encryption and push the fine-grained level of ROI video encryption to the minimum $8\times8$ CU precision. The experimental results demonstrate that the proposed algorithm can accurately segment ROI regions, effectively perturb pixels within these regions, and eliminate the diffusion artifacts introduced by encryption. The method exhibits great potential for application in medical imaging, military surveillance, and remote areas.