提出可处理时间偏移与拉伸的非负矩阵分解方法,提升脑组织分层精度。
Shift- and stretch-invariant non-negative matrix factorization with an application to brain tissue delineation in emission tomography data
- 在频域中建模时间偏移与拉伸,通过相位调整和零填充实现
- 在合成数据与真实脑部发射数据上显著改善组织结构解析
- 适合动态神经影像分析,尤其对血流或脑脊液示踪剂研究者
动态神经影像数据(如放射性示踪剂在血液或脑脊液中的传输测量)常呈现类扩散特性,导致距离相关的时序延迟、尺度差异和时间拉伸,限制了传统线性建模与分解方法的效果。为此,我们提出一种抗平移与拉伸的非负矩阵分解框架。该方法在频域中同时估计整数与非整数时间偏移及时间拉伸,其中偏移对应相位变化,拉伸通过零填充或截断处理。模型基于PyTorch实现(https://github.com/anders-s-olsen/shiftstretchNMF)。在合成数据与脑部发射断层扫描数据上的实验表明,该方法能有效建模时间拉伸,提供更精细的脑组织结构表征。
原文摘要 · Abstract (English)
Dynamic neuroimaging data, such as emission tomography measurements of radiotracer transport in blood or cerebrospinal fluid, often exhibit diffusion-like properties. These introduce distance-dependent temporal delays, scale-differences, and stretching effects that limit the effectiveness of conventional linear modeling and decomposition methods. To address this, we present the shift- and stretch-invariant non-negative matrix factorization framework. Our approach estimates both integer and non-integer temporal shifts as well as temporal stretching, all implemented in the frequency domain, where shifts correspond to phase modifications, and where stretching is handled via zero-padding or truncation. The model is implemented in PyTorch (https://github.com/anders-s-olsen/shiftstretchNMF). We demonstrate on synthetic data and brain emission tomography data that the model is able to account for stretching to provide more detailed characterization of brain tissue structure.
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