发现大模型生成有害内容有特定参数机制，可精准清除而不影响正常功能。

Large language models remain vulnerable to jailbreaks that elicit harmful responses, yet the mechanism behind harmful response generation is poorly understood. Here, we investigate how this capability is organized within model parameters. We identify and prune parameters that specifically support harmful compliance, providing a direct mechanistic analysis at the parameter level. We find that this capability depends on a sparse set of critical parameters: pruning these parameters substantially reduces harmful compliance while causing only limited degradation in benign capabilities, suggesting that key components of harmful generation are separable from those of general utility. Parameters identified from one harm category also reduce harmful responses in others, indicating components shared across harm types. This separability appears primarily in aligned models, suggesting that alignment training internally reshapes the harmful response mechanism even when behavioral safeguards remain brittle. We further show that harmful response generation is dissociable from the ability to recognize and reason about harmfulness. Finally, we extend our analysis to emergent misalignment and identify a sparse set of parameters contributing to it, with substantial sharing across fine-tuning domains. Together, these results reveal a consistent parameter-level organization underlying unsafe behaviors and point toward more principled interventions for improving model safety.