arXiv:2604.10303cs.CV2026-04

通过解耦影像质量概念,实现心房LGE-MRI的弱监督质量评估。

AC-MIL: Weakly Supervised Atrial LGE-MRI Quality Assessment via Adversarial Concept Disentanglement

  • 将图像质量分解为临床可解释的概念,提升评估透明度。
  • 在真实临床数据上实现与顶尖方法相当的分级准确率。
  • 适合需要可解释性诊断辅助的临床医生和医学AI研发者。

高质量晚钆增强(LGE)MRI对房颤管理至关重要,但常因患者运动、呼吸不规则及成像时机不当导致质量下降。尽管多实例学习(MIL)在弱监督下已用于自动质量评估,现有方法将局部视觉证据映射为单一、不可解释的全局特征向量,无法提供具体问题的反馈,难以判断扫描劣化是由于运动模糊、对比度不足还是解剖上下文缺失。本文提出对抗概念解耦的多实例学习(AC-MIL),仅使用体积级别标签,将整体图像质量分解为临床定义的放射学概念。为捕捉潜在质量差异而不纠缠预设概念,框架引入无监督残差分支,并通过对抗擦除机制严格防止信息泄露。同时,设计空间多样性约束,惩罚不同概念注意力图之间的重叠,确保特征提取的局部性和可解释性。在心房LGE-MRI体积的临床数据集上,实验表明AC-MIL成功打开MIL黑箱,生成高度局部化的空间概念图,帮助临床医生精确定位非诊断性扫描的具体原因。关键的是,该框架在保持高度临床可解释性的同时,实现了与现有基线相当的序数分级性能。代码将在接受后发布。

原文摘要 · Abstract (English)

High-quality Late Gadolinium Enhancement (LGE) MRI can be helpful for atrial fibrillation management, yet scan quality is frequently compromised by patient motion, irregular breathing, and suboptimal image acquisition timing. While Multiple Instance Learning (MIL) has emerged as a powerful tool for automated quality assessment under weak supervision, current state-of-the-art methods map localized visual evidence to a single, opaque global feature vector. This black box approach fails to provide actionable feedback on specific failure modes, obscuring whether a scan degrades due to motion blur, inadequate contrast, or a lack of anatomical context. In this paper, we propose Adversarial Concept-MIL (AC-MIL), a weakly supervised framework that decomposes global image quality into clinically defined radiological concepts using only volume-level supervision. To capture latent quality variations without entangling predefined concepts, our framework incorporates an unsupervised residual branch guided by an adversarial erasure mechanism to strictly prevent information leakage. Furthermore, we introduce a spatial diversity constraint that penalizes overlap between distinct concept attention maps, ensuring localized and interpretable feature extraction. Extensive experiments on a clinical dataset of atrial LGE-MRI volumes demonstrate that AC-MIL successfully opens the MIL black box, providing highly localized spatial concept maps that allow clinicians to pinpoint the specific causes of non-diagnostic scans. Crucially, our framework achieves this deep clinical transparency while maintaining highly competitive ordinal grading performance against existing baselines. Code to be released on acceptance.

医学影像弱监督可解释性

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