arXiv:2604.10389cs.CL2026-04中稿 · the IEEE Internati…被引 1

用多智能体辩论+检索增强,精准发现临床术语替换错误。

BLUEmed: Retrieval-Augmented Multi-Agent Debate for Clinical Error Detection

论文配图:BLUEmed: Retrieval-Augmented Multi-Agent Debate for Clinical Error Detection
图 1 · 摘自论文原文
  • 拆分病历为子问题,通过多重检索获取证据,双专家独立分析。
  • 少样本下准确率69.13%,AUC达74.45%,优于单智能体与纯辩论方法。
  • 适合医疗文本纠错、需高可靠性的临床AI系统使用。

临床笔记中的术语替换错误(一个语言上合法但临床意义不同的词被误用)是自动化检测的长期挑战。我们提出BLUEmed,一种融合混合检索增强生成(RAG)的多智能体辩论框架,结合证据驱动推理与多视角验证以实现临床错误检测。BLUEmed将每条临床笔记分解为聚焦子查询,通过密集、稀疏及在线检索获取源分区证据,并分配两名领域专家智能体使用不同知识库进行独立分析;当专家意见不一致时,通过结构化反驳与跨源仲裁解决冲突,随后由级联安全层过滤常见假阳性模式。我们在零样本与少样本提示下,基于多个主流模型(包含专有与开源家族)评估BLUEmed。实验表明,在少样本提示下,BLUEmed达到最高准确率(69.13%)、ROC-AUC(74.45%)与PR-AUC(72.44%),显著优于单智能体RAG与纯辩论基线。对六种骨干模型与两种提示策略的进一步分析证实,检索增强与结构化辩论具有互补性,且该框架在具备足够指令遵循与临床语言理解能力的模型上收益最大。

原文摘要 · Abstract (English)

Terminology substitution errors in clinical notes, where one medical term is replaced by a linguistically valid but clinically different term, pose a persistent challenge for automated error detection in healthcare. We introduce BLUEmed, a multi-agent debate framework augmented with hybrid Retrieval-Augmented Generation (RAG) that combines evidence-grounded reasoning with multi-perspective verification for clinical error detection. BLUEmed decomposes each clinical note into focused sub-queries, retrieves source-partitioned evidence through dense, sparse, and online retrieval, and assigns two domain expert agents distinct knowledge bases to produce independent analyses; when the experts disagree, a structured counter-argumentation round and cross-source adjudication resolve the conflict, followed by a cascading safety layer that filters common false-positive patterns. We evaluate BLUEmed on a clinical terminology substitution detection benchmark under both zero-shot and few-shot prompting with multiple backbone models spanning proprietary and open-source families. Experimental results show that BLUEmed achieves the best accuracy (69.13%), ROC-AUC (74.45%), and PR-AUC (72.44%) under few-shot prompting, outperforming both single-agent RAG and debate-only baselines. Further analyses across six backbone models and two prompting strategies confirm that retrieval augmentation and structured debate are complementary, and that the framework benefits most from models with sufficient instruction-following and clinical language understanding.

医疗AI错误检测多智能体RAG

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