提出新模型抑制血管造影运动伪影,提升图像清晰度。
VCC-DSA: A Novel Vascular Consistency Constrained DSA Imaging Model for Motion Artifact Suppression
- 设计学习型减影范式,解决算法不稳定问题。
- 通过残差密集块与细节捷径,增强复杂结构表现。
- 创新血管一致性策略,自动提取血管特征并抑制伪影。
数字减影血管造影(DSA)是诊断脑血管疾病的金标准,但高衰减组织(如骨骼、牙齿、导管)运动导致的伪影严重降低血管可见性。本文提出新型血管一致性约束的DSA成像模型(VCC-DSA),通过四项设计实现鲁棒运动抑制与精准血管成像:1)设计基于学习的减影映射范式,解决现有学习方法病态问题,提升算法稳定性;2)引入残差密集块与细节捷径,在骨骼重叠、微小外周血管等复杂结构下提升性能;3)提出创新的血管一致性策略,从掩码-活体图像中相对运动中自发提取内在一致性,自动分离对比剂显影的血管结构,有效抑制运动伪影,并缓解数据配准要求;4)设计基于Mixup的数据自演化策略,在训练过程中动态优化数据,强化血管特征学习,剔除无关结构及标签中的伪结构/伪影。前瞻性地,除人类临床数据评估外,还开展全身麻醉动物实验验证实用性。相比其他方法,本模型在PSNR和SSIM上分别提升73.4%和8.56%。
原文摘要 · Abstract (English)
Digital Subtraction Angiography (DSA) is a clinically significant imaging technique for diagnosing cerebrovascular disease, as gold-standard. However, the artifacts caused by motion of high-attenuation tissues such as bones, teeth, and catheters, seriously reduce the visibility of blood vessels. This paper presents a novel Vascular Consistency Constrained DSA Imaging Model (VCC-DSA) for robust motion suppression and precise vascular imaging with the following designs: 1) We specially design a Learning-based Subtraction Mapping Paradigm, so that the ill-posed problem of existing learning-based methods can be solved to enhance the stability of the algorithm. 2) Our model effectively develops Residual Dense Blocks and details-shortcut to improve the performance under complex structures, such as moving bones overlapping with blood vessels, and small features, like peripheral vessels. 3) An innovative Vascular Consistency Strategy is proposed to extract intrinsically consistency from the various relative motions in mask-live images, so that spontaneously distils the vascular structure with contrast-agent development and robustly suppress motion artifacts, and also naturally alleviates the high matching requirements of data. 4) We creatively design a Mixup-based Data Self-evolution Strategy for data-intra self-enhancement in training loop, so that the training data gains dynamically optimized to promote model better learning the vascular features, and excluding the irrelevant structures in live/mask image and even the inevitable-artifacts/fake-structure in label. Prospectively, to further evaluate practical value, an actual general anesthesia animal experiment is specially conducted, besides the assessment on human clinical data. Compared with other method, our model improves the PSNR and SSIM by 73.4% and 8.56%, respectively.
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