提出微操作新框架,解决生物微对象操控中的感知与控制难题。
Micro-Dexterity in Biological Micromanipulation: Embodiment, Perception, and Control

- 从本体、感知、控制三方面重构微尺度操作逻辑
- 揭示现有实验与临床应用间操作精度差距
- 适合微机器人、生物工程领域研究者参考
微尺度操控在受控运动与靶向运输方面已取得显著进展,但许多生物医学应用仍需对生物微对象进行精确且自适应的交互。在该尺度下,操控主要依赖三类平台:物理接触式微机器人、场驱动无接触捕获系统以及远程驱动的外部执行器。与宏观操纵不同,这些系统工作在流体、受限且表面主导的环境中,具有惯性可忽略、界面力占主导、目标柔软异质脆弱等特点。因此,传统灵巧操控假设——刚体接触、稳定抓握、丰富本体感知反馈——难以维持。本文提出‘微灵巧性’(micro-dexterity)框架,通过本体、感知与控制的协同作用分析生物微操控。探讨推、重定向、抓握及协作操作等经典操作范式在微尺度下的重构方式;对比基于接触的微操纵器、无接触场驱动系统及协作多智能体平台的架构差异;综述任务执行所需感知与控制策略。识别出实验室演示与临床相关生物操控间的当前灵巧性差距,并指出未来转化的关键挑战。
原文摘要 · Abstract (English)
Microscale manipulation has advanced substantially in controlled locomotion and targeted transport, yet many biomedical applications require precise and adaptive interaction with biological micro-objects. At these scales, manipulation is realized through three main classes of platforms: embodied microrobots that physically interact as mobile agents, field-mediated systems that generate contactless trapping or manipulation forces, and externally actuated end-effectors that interact through remotely driven physical tools. Unlike macroscale manipulators, these systems function in fluidic, confined, and surface-dominated environments characterized by negligible inertia, dominant interfacial forces, and soft, heterogeneous, and fragile targets. Consequently, classical assumptions of dexterous manipulation, including rigid-body contact, stable grasping, and rich proprioceptive feedback, become difficult to maintain. This review introduces micro-dexterity as a framework for analyzing biological micromanipulation through the coupled roles of embodiment, perception, and control. We examine how classical manipulation primitives, including pushing, reorientation, grasping, and cooperative manipulation, are reformulated at the microscale; compare the architectures that enable them, from contact-based micromanipulators to contactless field-mediated systems and cooperative multi-agent platforms; and review the perception and control strategies required for task execution. We identify the current dexterity gap between laboratory demonstrations and clinically relevant biological manipulation, and outline key challenges for future translation.
Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。