构建首个大规模骨科MRI原始数据集,助力模型跨部位泛化研究
MosaicMRI: A Diverse Dataset and Benchmark for Raw Musculoskeletal MRI

- 整合2671个骨骼肌影像体积,覆盖多部位、多序列、多线圈配置
- 联合训练模型在小样本下优于专一部位模型,揭示跨部位可迁移特性
- 发现足部与肘部等结构间存在强泛化能力,为临床部署提供依据
深度学习已广泛应用于MRI重建、伪影去除和分割等任务,但现有进展主要依赖脑部和膝关节的公开数据集,导致模型在多样解剖场景下的可靠性研究受限。本文提出MosaicMRI,是迄今最大的开源原始骨科肌肉骨骼(MSK)MRI数据集,包含2,671个体积和80,156张切片,涵盖轴位、矢状位等不同体位,以及PD、T1、T2等多种成像对比度,涉及脊柱、膝关节、髋关节、踝关节等多个解剖部位,且包含不同数量的接收线圈。以VarNet为基线,在加速重建任务中系统研究了模型容量与数据规模的扩展行为。结果显示,在小样本条件下,联合训练的模型显著优于专用于特定部位的模型,表明解剖多样性带来的跨部位相关性可被有效利用。进一步通过在脊柱上训练、在膝关节上测试等跨部位评估,发现如足部与肘部等特定组合具有良好的泛化性能,而域偏移下的表现受训练集规模、解剖部位及协议因素共同影响。
原文摘要 · Abstract (English)
Deep learning underpins a wide range of applications in MRI, including reconstruction, artifact removal, and segmentation. However, progress has been driven largely by public datasets focused on brain and knee imaging, shaping how models are trained and evaluated. As a result, careful studies of the reliability of these models across diverse anatomical settings remain limited. In this work, we introduce MosaicMRI, a large and diverse collection of fully sampled raw musculoskeletal (MSK) MR measurements designed for training and evaluating machine-learning-based methods. MosaicMRI is the largest open-source raw MSK MRI dataset to date, comprising 2,671 volumes and 80,156 slices. The dataset offers substantial diversity in volume orientation (e.g., axial, sagittal), imaging contrasts (e.g., PD, T1, T2), anatomies (e.g., spine, knee, hip, ankle, and others), and numbers of acquisition coils. Using VarNet as a baseline for accelerated reconstruction task, we perform a comprehensive set of experiments to study scaling behavior with respect to both model capacity and dataset size. Interestingly, models trained on the combined anatomies significantly outperform anatomy-specific models in low-sample regimes, highlighting the benefits of anatomical diversity and the presence of exploitable cross-anatomical correlations. We further evaluate robustness and cross-anatomy generalization by training models on one anatomy (e.g., spine) and testing them on another (e.g., knee). Notably, we identify groups of body parts (e.g., foot and elbow) that generalize well with each other, and highlight that performance under domain shifts depends on both training set size, anatomy, and protocol-specific factors.
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