arXiv:2604.17340cs.CL2026-04中稿 · AAAI

用符号逻辑自动发现多病共存时临床指南的冲突,提升AI诊疗可靠性。

Neuro-Symbolic Resolution of Recommendation Conflicts in Multimorbidity Clinical Guidelines

论文配图:Neuro-Symbolic Resolution of Recommendation Conflicts in Multimorbidity Clinical Guidelines
图 1 · 摘自论文原文
  • 将临床文本转为逻辑语言,用SAT求解器验证规则一致性。
  • 90.6%的冲突是多病交叠导致的局部矛盾,传统指南无法应对。
  • 相比大模型,该方法检测冲突的准确率提升至F1=0.861,适合医疗AI系统开发者。

临床指南由不同专科协会独立制定,普遍存在碎片化、冗余和逻辑矛盾。这些不一致在多病共存患者中尤为严重,不仅引发医生认知失调,还使标准检索增强生成(RAG)系统脆弱易幻觉。为解决这一根本可靠性危机,我们提出一种神经符号框架,自动化检测推荐冗余与冲突。该流程采用多智能体系统将非结构化临床自然语言转化为严格符号逻辑语言,并由可满足性(SAT)求解器验证。通过构建层级化的逻辑规则交互分类体系,识别出一类关键冲突——局部冲突(Local Conflict),即多种共病交叉导致的决策冲突。在包含12个权威SGLT2抑制剂指南的定制基准上评估,发现90.6%的冲突属于此类。现有先进大模型无法有效检测,而本方法取得F1分数0.861。结果表明,逻辑验证应先于信息检索,为医疗AI中的知识协调树立新标准。

原文摘要 · Abstract (English)

Clinical guidelines, typically developed by independent specialty societies, inherently exhibit substantial fragmentation, redundancy, and logical contradiction. These inconsistencies, particularly when applied to patients with multimorbidity, not only cause cognitive dissonance for clinicians but also introduce catastrophic noise into AI systems, rendering the standard Retrieval-Augmented Generation (RAG) system fragile and prone to hallucination. To address this fundamental reliability crisis, we introduce a Neuro-Symbolic framework that automates the detection of recommendation redundancies and conflicts. Our pipeline employs a multi-agent system to translate unstructured clinical natural language into rigorous symbolic logic language, which is then verified by a Satisfiability (SAT) solver. By formulating a hierarchical taxonomy of logical rule interactions, we identify a critical category termed Local Conflict - a decision conflict arising from the intersection of comorbidities. Evaluating our system on a curated benchmark of 12 authoritative SGLT2 inhibitor guidelines, we reveal that 90.6% of conflicts are Local, a structural complexity that single-disease guidelines fail to address. While state-of-the-art LLMs fail in detecting these conflicts, our neuro-symbolic approach achieves an F1 score of 0.861. This work demonstrates that logical verification must precede retrieval, establishing a new technical standard for automated knowledge coordination in medical AI.

医疗AI逻辑推理知识融合多病共存

Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。