用加权知识蒸馏提升口腔全景片上颌窦分割精度
Weighted Knowledge Distillation for Semi-Supervised Segmentation of Maxillary Sinus in Panoramic X-ray Images

- 通过加权蒸馏损失抑制教师与学生预测差异带来的错误信号
- 在2511例患者数据上达到96.35%的Dice分数,边界误差显著降低
- 适合标注数据少但需高精度分割的牙科影像分析场景
准确分割全景牙片中的上颌窦对牙科诊断和手术规划至关重要,但因结构重叠、解剖边界模糊及高质量像素级标注数据稀缺,该任务在牙科影像研究中仍较受忽视。为此,我们提出一种半监督分割框架,有效利用有标签和无标签全景牙片,通过知识蒸馏将教师模型的可靠结构信息传递给学生模型。具体地,引入加权知识蒸馏损失以抑制教师与学生预测间结构差异导致的不可靠蒸馏信号。为进一步提升教师网络生成伪标签的质量,设计了基于非配对图像到图像转换的SinusCycle-GAN精修网络,改善边界精度并减少无标签数据学习过程中的噪声传播。在采集自2511名患者的临床全景牙片数据集上评估,实验结果表明所提方法优于现有先进模型,达到96.35%的Dice分数,同时降低边界误差。结果表明,该半监督框架在标注数据有限条件下仍能提供鲁棒且解剖一致的分割性能,具有广泛牙科影像分析应用潜力。
原文摘要 · Abstract (English)
Accurate segmentation of maxillary sinus in panoramic X-ray images is essential for dental diagnosis and surgical planning; however, this task remains relatively underexplored in dental imaging research. Structural overlap, ambiguous anatomical boundaries inherent to two-dimensional panoramic projections, and the limited availability of large scale clinical datasets with reliable pixel-level annotations make the development and evaluation of segmentation models challenging. To address these challenges, we propose a semi-supervised segmentation framework that effectively leverages both labeled and unlabeled panoramic radiographs, where knowledge distillation is utilized to train a student model with reliable structural information distilled from a teacher model. Specifically, we introduce a weighted knowledge distillation loss to suppress unreliable distillation signals caused by structural discrepancies between teacher and student predictions. To further enhance the quality of pseudo labels generated by the teacher network, we introduce SinusCycle-GAN which is a refinement network based on unpaired image-to-image translation. This refinement process improves the precision of boundaries and reduces noise propagation when learning from unlabeled data during semi-supervised training. To evaluate the proposed method, we collected clinical panoramic X-ray images from 2,511 patients, and experimental results demonstrate that the proposed method outperforms state-of-the-art segmentation models, achieving the Dice score of 96.35\% while reducing boundary error. The results indicate that the proposed semi-supervised framework provides robust and anatomically consistent segmentation performance under limited labeled data conditions, highlighting its potential for broader dental image analysis applications.
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