arXiv:2604.24793eess.IVcs.CV2026-04

统一分割结直肠癌多模态影像,高效适配不同数据类型。

CRC-SAM: SAM-Based Multi-Modal Segmentation and Quantification of Colorectal Cancer in CT, Colonoscopy, and Histology Images

论文配图:CRC-SAM: SAM-Based Multi-Modal Segmentation and Quantification of Colorectal Cancer in CT, Colonoscopy, and Histology Images
图 1 · 摘自论文原文
  • 基于MedSAM框架,用轻量级LoRA层适配不同医学影像模态。
  • 在三种数据集上均优于现有方法,尤其在小样本模态表现突出。
  • 适合临床全流程使用,特别适用于数据稀缺的影像分析场景。

我们提出CRC-SAM,一种统一的结直肠癌分割框架,可处理结肠镜、CT及组织病理图像。不同于以往单模态方法,CRC-SAM在整个临床流程中提供一致且模态无关的分割结果。该框架以MedSAM为基础,将低秩适应(LoRA)层引入冻结编码器,实现对低资源模态的高效域迁移,仅需极少可训练参数。在MSD-Colon、CVC-ClinicDB和EBHI-Seg数据集上的实验表明,其跨模态性能显著优于现有先进方法,验证了基于基础模型的轻量级LoRA适配在结直肠癌分析中的有效性。

原文摘要 · Abstract (English)

We present CRC-SAM, a unified framework for colorectal cancer segmentation across colonoscopy, CT, and histopathology images. Unlike prior single-modality methods, CRC-SAM provides consistent, modality-agnostic segmentation throughout the clinical workflow. Built on MedSAM, it incorporates low-rank adaptation (LoRA) layers into a frozen encoder, enabling efficient domain transfer to underrepresented modalities with minimal trainable parameters. Experiments on MSD-Colon, CVC-ClinicDB, and EBHI-Seg demonstrate superior performance across modalities, outperforming state-of-the-art baselines and highlighting the effectiveness of lightweight LoRA adaptation for foundation-model-based colorectal cancer analysis.

医学影像分割多模态LoRA

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