arXiv:2605.05214eess.SPcs.AI2026-05

用生理信号规律设计模型,高效处理心电脑电数据分类

MedMamba: Recasting Mamba for Medical Time Series Classification

论文配图:MedMamba: Recasting Mamba for Medical Time Series Classification
图 1 · 摘自论文原文
  • 基于生理信号的时空特性,设计多尺度双向状态空间结构
  • 在6个数据集上表现优于现有方法,最长序列任务准确率达85.97%
  • 推理速度提升4.6倍,适合临床实时应用

医学时间序列如心电图(ECG)和脑电图(EEG)具有复杂的时序动态和跨通道结构依赖关系,给自动化分析带来挑战。传统卷积与循环模型难以捕捉长程依赖,而基于Transformer的方法存在二次复杂度问题,且引入冗余交互,与生理信号内在结构不匹配。为此,我们提出MedMamba,一种基于生理信号三大先验假设(空间集中性、多时标时序组合、非因果上下文依赖)的轻量级多尺度双向状态空间架构。通过通道混合模块实现跨通道重参数化,多尺度卷积标记化进行时序分解,双向Mamba块以线性复杂度建模全局上下文。在涵盖EEG、ECG和人体活动信号的六个基准数据集上实验表明,MedMamba在多种模态下持续优于先进方法。特别地,在挑战性数据集ADFTD上取得54.72%准确率和52.01% F1分数,创下新纪录;在长序列数据集SleepEDF上也表现优异。此外,推理速度提升4.6倍,验证其在真实临床部署中的实用性。结果表明,基于原理引导的状态空间建模为医学时间序列分析提供了有效且可扩展的替代方案。

原文摘要 · Abstract (English)

Medical time series, such as electrocardiograms (ECG) and electroencephalograms (EEG), exhibit complex temporal dynamics and structured cross-channel dependencies, posing fundamental challenges for automated analysis. Conventional convolutional and recurrent models struggle to capture long-range dependencies, while Transformer-based approaches incur quadratic complexity and often introduce redundant interactions that are misaligned with the intrinsic structure of physiological signals. To address these limitations, we propose MedMamba, a principle-driven multi-scale bidirectional state space architecture tailored for medical time series classification. Our design is guided by three key inductive biases of physiological signals: spatial centralization, multi-timescale temporal composition, and non-causal contextual dependency. These principles are instantiated through a lightweight channel-mixing module for cross-channel reparameterization, multi-scale convolutional tokenization for temporal decomposition, and bidirectional Mamba blocks for efficient global context modeling with linear complexity. Extensive experiments on six benchmark datasets spanning EEG, ECG, and human activity signals demonstrate that MedMamba consistently outperforms state-of-the-art methods across diverse modalities. Notably, it achieves 85.97% accuracy on PTB and establishes new state-of-the-art performance on the challenging ADFTD dataset (54.72% accuracy and 52.01% F1-score). Strong results on long-sequence benchmarks, such as SleepEDF, further validate its capability in modeling long-range dependencies. Moreover, MedMamba achieves a speedup of 4.6x in inference, highlighting its practicality for real-time clinical deployment. These results suggest that principle-guided state space modeling offers an effective and scalable alternative to Transformer-based approaches for medical time series analysis.

医疗时序状态空间模型效率多尺度建模

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