让大规模多智能体系统在资源约束下自适应协调，无需重训即可应对群体结构变化。

In large-scale multi-agent systems with shared resource constraints, an upstream planner must iteratively evaluate candidate resource plans -- assessing feasibility, aggregate response, and marginal cost -- before committing to one. Lagrangian relaxation separates local decisions through a broadcast cost signal, but the planner still needs the cost-to-utilization response map to explore plan space, and this map depends on population composition that changes across planning cycles. We propose \emph{population-aware coordination interfaces}: learned primal and dual maps, conditioned on compact population summaries, that the planner queries inside its iterative loop. The primal map predicts aggregate utilization under a proposed cost trajectory; the dual map predicts the cost trajectory for a target plan. By encoding response-relevant population structure, these maps remain reliable across evolving populations without per-cycle retraining, and support coordination of large populations from compact subsamples. We additionally cast Sim2Real transfer as a backtestable procedure, enabling evaluation before deployment. In a supply-chain capacity-control case study, population-aware interfaces reduce forecast error by 16--19\% and capacity violations by 20--51\% relative to population-unaware baselines under composition shift; 20K-agent cohorts support accurate coordination of 500K-agent populations; and simulator-trained primal maps achieve 11.1\% MAPE on real observations versus 13--24\% for baselines.