通过分散学习提升医学图像细粒度分割精度
Med-DisSeg: Dispersion-Driven Representation Learning for Fine-Grained Medical Image Segmentation

- 用批内表示作负样本,增强特征分散性
- 在五大数据集上达到顶尖分割效果
- 适合器官轮廓模糊的医学图像分析
精准医学影像分割对个性化医疗至关重要,但异质外观、边界模糊和解剖变异仍带来挑战。目标结构与周围组织常具有相似强度与纹理,导致激活模糊、分割不可靠。我们发现根源在于编码过程中的表征坍塌和解码阶段缺乏细粒度多尺度校准。为此提出Med-DisSeg,一种基于分散驱动的医学图像分割框架,联合优化表征学习与解剖结构勾画。该方法结合轻量级分散损失(Dispersive Loss)与自适应注意力机制,通过将批次内隐藏表示视为负样本,扩大样本间距离,生成分布更散、边界敏感的嵌入,开销极小。基于增强表征,编码器强化结构响应,解码器实现自适应多尺度校准,保留局部纹理与全局形状信息。在涵盖三种成像模态的五个数据集上进行大量实验,结果持续领先当前最优水平。此外,该模型在多器官CT分割任务中也表现优异,验证了其鲁棒性与跨任务适用性。
原文摘要 · Abstract (English)
Accurate medical image segmentation is fundamental to precision medicine, yet robust delineation remains challenging under heterogeneous appearances, ambiguous boundaries, and large anatomical variability. Similar intensity and texture patterns between targets and surrounding tissues often lead to blurred activations and unreliable separation. We attribute these failures to representation collapse during encoding and insufficient fine grained multi scale decoding. To address these issues, we propose Med DisSeg, a dispersion driven medical image segmentation framework that jointly improves representation learning and anatomical delineation. Med DisSeg combines a lightweight Dispersive Loss with adaptive attention for fine grained structure segmentation. The Dispersive Loss enlarges inter sample margins by treating in batch hidden representations as negative pairs, producing well dispersed and boundary aware embeddings with negligible overhead. Based on these enhanced representations, the encoder strengthens structure sensitive responses, while the decoder performs adaptive multi scale calibration to preserve complementary local texture and global shape information. Extensive experiments on five datasets spanning three imaging modalities demonstrate consistent state of the art performance. Moreover, Med DisSeg achieves competitive results on multi organ CT segmentation, supporting its robustness and cross task applicability.
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