提出形态-模态框架,揭示生物信号波形结构如何决定模型设计。
Modality vs. Morphology: A Framework for Time Series Classification for Biological Signals

- 构建形态与模态的统一框架,连接波形特征与建模方法
- 发现形态比模型类型更关键,直接影响性能与可解释性
- 适合生理信号分析、可解释模型设计的研究者参考
生物信号的时间序列分类已从手工设计的模态特定方法,发展为能捕捉生理过程复杂波形结构(即形态)的深度模型。本文提出一个统一的形态-模态框架,将波形结构(如尖峰、爆发、振荡、缓慢漂移、层级节律)与方法设计相联系,揭示其如何指导预处理与建模策略。通过对脑电图(EEG)、肌电图(EMG)、心电图(ECG)、光电容积脉搏波(PPG)及眼动模态(视网膜电图、瞳孔测量、眼动追踪)的分析,框架表明:形态而非模型类别,是决定性能与可解释性的核心因素。这解释了为何当深度模型的归纳偏置与波形动态一致时,表现更优。研究还指出未来方向,包括形态数据增强与评估指标,以提升泛化能力。这些见解推动形态感知建模成为跨生物信号时间序列分类中通用、可解释且生理意义明确的统一原则。
原文摘要 · Abstract (English)
Time series classification (TSC) of biological signals has progressed from handcrafted, modality-specific approaches to deep architectures capable of representing the diverse waveform structures of underlying physiological processes (i.e., morphology). This review introduces a unified morphology--modality framework that connects waveform structure to a methodological design, revealing how spikes, bursts, oscillations, slow drift, and hierarchical rhythms inform model design. By analyzing electroencephalography, electromyography, electrocardiography, photoplethysmography, and ocular modalities (electrooculography, pupillometry, eye-tracking), the review demonstrates how morphology determines preprocessing and modeling strategies. Integrating evidence across these biological signals, the framework reveals that morphology, not model class, most strongly determines performance and interpretability. This provides insight into why deep models succeed when their inductive biases align with underlying waveform dynamics. This review also identifies future work including morphological data augmentation and evaluation metrics to improve generalization. Together, these insights position morphology-aware modeling as a unifying principle for developing generalizable, interpretable, and physiologically meaningful TSC models across biological signals.
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