用局部可塑性实现高效语音分离，生物可解释性强。

Blind source separation (BSS) is a natural framework for studying how latent causes may be recovered from sensory mixtures, but deriving online and biologically plausible algorithms for structured (i.e., constrained to known domains) and potentially correlated sources remains challenging. Recent work has derived neural networks for BSS from maximization of an entropy measure, yet its online implementations involve complex and nonlocal recurrent dynamics. Motivated by this perspective, we propose Predictive Entropy Maximization, which achieves competitive performance in BSS, using only local weight updates. The method employs a close approximation of an entropy measure, yielding an objective function with easily interpretable components. Minimizing this objective leads to a predictive neural architecture in which feedforward synapses follow an error-driven rule (that can be realized through dendritic mechanisms), lateral inhibitory connections are learned with local Hebbian plasticity, and source-domain constraints are enforced through simple output nonlinearities. We derive explicit spectral bounds on the surrogate error, characterizing when the approximation is accurate. Empirically, Predictive Entropy Maximization remains robust under increasing source correlation and observation noise, outperforms biologically plausible algorithms that rely on stronger independence or decorrelation assumptions, and remains competitive with exact determinant- and correlative-information-based baselines. These results show how local plasticity and adaptive lateral inhibition can emerge from maximizing a regularized second-order entropy over structured source domains. Our implementation code is available at https://github.com/BariscanBozkurt/Predictive-Entropy-Maximization.