无需训练,按结构拆解文章生成准确医学摘要。
Divide-Prompt-Refine: a Training-Free, Structure-Aware Framework for Biomedical Abstract Generation

- 分步处理:按背景-目的-方法-结果-结论结构拆解文本
- 在46,309篇论文上超越现有方法,保持事实一致性
- 适合低资源场景下快速生成高质量医学摘要
医学摘要在信息检索、生物数据注释和知识发现等下游NLP任务中至关重要,但大量医学文献缺乏摘要,限制了其应用价值。我们提出DPR-BAG(Divide-Prompt-Refine for Biomedical Abstract Generation),一种无需训练的零样本框架,可为无摘要的全文生成连贯且事实准确的摘要。该框架遵循背景-目的-方法-结果-结论(BOMRC)结构,将全文分解为若干语用模块,对每个模块并行使用大模型进行摘要,最后通过精炼阶段恢复整体语篇连贯性。在包含46,309篇文献的分布对齐数据集PMC-MAD上,DPR-BAG在抽象新颖性上优于强提取基线与微调模型,同时保持事实一致性。消融实验揭示反直觉现象:增加提示复杂度或显式注入实体引导反而降低事实对齐度,凸显受控提示策略的重要性。研究证明,无需训练、结构感知的框架在低资源场景下具有规模化生成医学摘要的巨大潜力。数据与代码已公开于Hugging Face与GitHub。
原文摘要 · Abstract (English)
Biomedical abstracts play a critical role in downstream NLP applications, such as information retrieval, biocuration, and biomedical knowledge discovery. However, a non-trivial number of biomedical articles do not have abstracts, diminishing the utility of these articles for downstream tasks. We propose DPR-BAG (Divide, Prompt, and Refine for Biomedical Abstract Generation), a training-free, zero-shot framework that generates coherent and factually grounded abstracts for biomedical articles with full text but no abstract. DPR-BAG decomposes full-text documents into structured rhetorical facets following the Background-Objective-Methods-Results-Conclusions (BOMRC) schema, performs parallel LLM-based summarization for each facet, and applies a final refinement stage to restore global discourse coherence. On PMC-MAD, a distribution-aligned dataset of 46,309 biomedical articles, DPR-BAG improves abstractive novelty over strong extractive and fine-tuned baselines, while maintaining factual consistency. Our ablation study reveals a counterintuitive finding: increasing prompt complexity or explicitly injecting entity-level guidance can degrade factual alignment, highlighting the importance of controlled prompting strategies. These findings underscore the potential of training-free, structure-aware frameworks for scalable biomedical abstract generation in low-resource settings. Our data and code are available at https://huggingface.co/datasets/pmc-mad/PMC-MAD and https://github.com/ScienceNLP-Lab/MultiTagger-v2/tree/main/DPR-BAG.
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