arXiv:2605.20751cs.LGcs.AI2026-05

用伪数据提升血糖控制评估精度,让稀疏自测血糖更可用

PACD-Net: Pseudo-Augmented Contrastive Distillation for Glycemic Control Estimation from SMBG

论文配图:PACD-Net: Pseudo-Augmented Contrastive Distillation for Glycemic Control Estimation from SMBG
图 1 · 摘自论文原文
  • 用伪SMBG数据做教师信号,指导稀疏血糖数据学习
  • 多视角对比学习增强模型在不同采样模式下的稳定性
  • 适合糖尿病管理、医疗传感数据建模等场景

有效的糖尿病管理需持续监测血糖水平。临床常用Time in Range (TIR)、Time Below Range (TBR)、Time Above Range (TAR)等指标评估血糖控制,通常来自连续血糖监测(CGM)。但许多患者因成本高、可及性差,仅依赖自测血糖(SMBG)。SMBG数据稀疏且不规则,传统监督学习难以准确估计上述指标,泛化能力差、性能不稳定。为此,本文提出PACD-Net:一种基于伪增强对比知识蒸馏的自监督框架,用于从SMBG数据中估计血糖控制指标。利用具有更丰富时间覆盖的伪SMBG样本作为教师信号,指导稀疏观测的学习;同时采用多视角对比学习,强化不同采样模式下的表示一致性。模型采用Swin Transformer-CNN混合主干网络,捕捉稀疏SMBG序列中的时序依赖关系。实验表明,PACD-Net在真实世界SMBG数据上持续优于现有方法,在极稀疏观测条件下显著提升TAR、TIR、TBR估计的准确性、稳定性和泛化能力。该框架为临床SMBG解读提供实用工具,并可推广至其他稀疏不规则传感器数据的学习任务。

原文摘要 · Abstract (English)

Effective diabetes management requires continuous monitoring of glycemic levels. Clinically, glycemic control is assessed using metrics such as Time in Range (TIR), Time Below Range (TBR), and Time Above Range (TAR), typically derived from continuous glucose monitoring (CGM). However, many patients rely on self-monitoring of blood glucose (SMBG) due to the high cost and limited accessibility of CGM. Unlike CGM, SMBG provides sparse and irregular measurements, making accurate estimation of these metrics challenging. Conventional supervised learning approaches struggle under such sparsity, leading to poor generalization and unstable performance. To address this, we propose PACD-Net, a self-supervised contrastive knowledge distillation framework for estimating glycemic control from SMBG. Pseudo-SMBG samples with richer temporal coverage are used as teacher signals to guide learning from sparse observations. In addition, multi-view contrastive learning enforces representation consistency across diverse sampling patterns. The model adopts a hybrid Swin Transformer-CNN backbone to capture temporal dependencies in sparse SMBG sequences. Experimental results demonstrate that PACD-Net consistently outperforms existing methods in estimating TAR, TIR, and TBR from real-world SMBG data, achieving improved accuracy as well as enhanced stability and generalization under extremely sparse observation settings. The proposed framework provides a practical tool for clinical SMBG interpretation and offers a generalizable approach for learning from sparse and irregularly sampled sensor data in broader applications.

血糖预测自监督学习医疗AI稀疏数据

Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。