VEELA是用于肝脏血管分割的临床约束数据集,提升医学影像分析可靠性。
VEELA: A Clinically-Constrained Benchmark for Liver Vessel Segmentation in Computed Tomography Angiography

- 基于40例CTA扫描,采用多专家共识与可见性驱动标注策略
- 首次在真实临床约束下构建精细肝门静脉血管分割数据集
- 提供多维度评估指标,适合医学影像算法开发与验证
对比增强计算机断层扫描血管造影(CTA)中肝脏与门脉血管的精确分割仍具挑战,受限于复杂血管拓扑、远端可视性差及成像诱导的模糊性。现有公开数据集虽有价值,但缺乏临床真实标注约束。本文提出VEELA(Vessel Extraction and Extrication for Liver Analysis),源自CHAOS挑战赛的40例CTA扫描,所有血管均在多专家共识下逐切片手动勾画,遵循严格可见性驱动标注规则,避免解剖学推断插值。该设计明确捕捉解剖变异与成像不确定性。作为CHAOS挑战的延续,VEELA支持可重复的跨基准评估,并扩展至细粒度肝门静脉分割。我们建立标准化基准框架,分析多种互补评估指标:拓扑感知(clDice)、重叠率(IoU)、边界敏感(NSD)和几何感知(面积、长度)。结果表明不同指标反映血管完整性的不同方面,强调多视角评估对临床意义分割的必要性。VEELA已公开发布,供研究者访问评估指标、数据集与提交平台:https://www.synapse.org/Synapse:syn65471967。
原文摘要 · Abstract (English)
Accurate segmentation of hepatic and portal vessels in contrast-enhanced computed tomography angiography (CTA) remains challenging due to complex vascular topology, peripheral visibility limitations, and acquisition-induced ambiguities. While existing public datasets offer valuable benchmarks, few include clinically realistic annotation constraints. We introduce VEELA (Vessel Extraction and Extrication for Liver Analysis), a rigorously curated liver vessel dataset derived from 40 CTA scans inherited from the CHAOS grand-challenge cohort. All vessels were manually delineated slice-by-slice under multi-expert consensus, using a strict visibility-driven annotation policy and avoiding anatomically inferred interpolation. This design explicitly captures anatomical variability and imaging-related uncertainty. As a continuation of the CHAOS challenge, VEELA enables reproducible cross-benchmark evaluation while extending the scope to fine-grained hepatic and portal vessel segmentation. We further establish a standardized benchmarking framework and analyze complementary evaluation metrics, including topology-aware (clDice), overlap-based (IoU), boundary-sensitive (NSD), and geometry-aware (area, length) measures. Our results demonstrate that different metrics capture distinct aspects of vascular integrity, underscoring the necessity of multi-perspective evaluation for clinically meaningful vessel segmentation. VEELA is publicly released to facilitate reproducible research and support the development of robust vascular segmentation methods. Researchers can access the evaluation metrics, dataset, and submission platform at https://www.synapse.org/Synapse:syn65471967.
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