arXiv:2605.22851eess.SPcs.LG2026-05

用可学习先验的扩散模型生成更真实的脉搏波形,还能还原生理特征。

VAMP-Diff: VampPrior Latent Diffusion for Photoplethysmography Modeling

论文配图:VAMP-Diff: VampPrior Latent Diffusion for Photoplethysmography Modeling
图 1 · 摘自论文原文
  • 结合编码器与条件扩散解码器,用可学习先验替代固定高斯先验。
  • 在CapnoBase数据集上重建波形更清晰,心率呼吸率保持一致。
  • 适合需要高保真生理信号建模的研究者和医疗健康应用开发者。

脉搏波描记(PPG)已成为一种广泛应用的生理信号;然而,现有生成模型仍难以保持真实波形形态,并学习能捕捉心脏与呼吸生理特性的潜在结构。基于对抗损失训练的生成器虽可产生合理波形,但缺乏从真实信号到潜在表示的推理路径。变分自编码器可将PPG数据映射至潜在码,但其解码器常模糊收缩期上升段并减弱振幅与频谱细节。扩散模型提升了波形保真度,但通常缺乏重建与生理分析所需的推理路径。本文提出VampPrior潜扩散模型(VAMP-Diff),一个联合训练的变分扩散模型,包含时序PPG编码器、条件一维扩散解码器以及对紧凑池化潜在变量的VampPrior正则化。该模型在扩散重建中使用完整时序潜在变量,使解码器能利用心跳节律与波形形态信息,同时从学习到的VampPrior组件中采样,而非固定高斯先验。在CapnoBase数据集上的实验表明,VAMP-Diff能生成真实感强的PPG信号,相比高斯先验基线重建出更锐利的生理波形,保持心率信息,维持呼吸率一致性,并通过重构误差对波形异常敏感。

原文摘要 · Abstract (English)

Photoplethysmography (PPG) has become a ubiquitous physiological signal; however, current generative models still struggle to preserve realistic waveform morphology and learn a latent structure that captures cardiac and respiratory physiology. PPG generators trained with adversarial losses can produce plausible waveforms, but provide no inference path from a real signal to a latent representation. Variational autoencoders, on the other hand, map the PPG data to latent codes, although their decoders often blur systolic upstrokes and dampen amplitude and spectral details. Diffusion models improve waveform fidelity, but typically lack an inference path for reconstruction and physiological analysis. We propose VampPrior Latent Diffusion (VAMP-Diff), a jointly trained variational diffusion model that combines a temporal PPG encoder, a conditional one-dimensional diffusion decoder, and VampPrior regularization on a compact pooled latent. The model uses full temporal latent during diffusion reconstruction, giving the decoder access to beat timing and morphology while generating samples from learned VampPrior components instead of a fixed Gaussian prior. We demonstrate on the CapnoBase dataset that VAMP-Diff produces realistic PPG signals, reconstructs sharper physiological waveforms than Gaussian-prior baselines, preserves heart-rate information, maintains respiratory-rate consistency, and is sensitive to waveform corruptions through reconstruction error.

生成模型生理信号扩散模型脉搏波

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