arXiv:2605.23917cs.CL2026-05被引 1

用多人辩论框架从文献中自动生成电池材料设计假说。

Multi-Persona Debate System for Automated Scientific Hypothesis Generation

  • 构建多角色代理,基于文献快照进行有依据的辩论。
  • 在钠离子负极和固态电池正极任务中生成可验证的设计逻辑。
  • 适合需要跨领域整合知识的科研人员使用。

现代科学发现的瓶颈不在于数据缺乏,而在于无法将碎片化知识整合为可行动的假设。这一挑战在电池材料研究中尤为突出,需同时优化电化学性能、界面行为与制造可行性。本文提出多人格辩论系统(MPDS),一种基于文献的自动化科学假说生成框架,融合文献检索、长上下文大模型推理、语料驱动的人格生成与结构化多智能体辩论。MPDS构建最多500篇论文的文献快照,使各代理基于角色特定证据池开展三轮有引文意识的辩论,并由主持人综合结果,实现观点协商同时保持证据可追溯性。我们采用时间控制协议评估MPDS,排除对目标论文的直接访问,包含两个独立的电池材料案例研究及30组匹配案例的盲评。在钠离子负极与全固态电池正极设计任务中,MPDS生成的设计逻辑与实验验证解空间一致,且比简单基线更机制明确、过程敏感。引入整合假说质量评分,消融实验表明,在五种条件下MPDS得分最高,尤其在跨视角整合上优势显著。实验室后续反馈显示其可作为诊断工具识别流程中的实际瓶颈。结果表明,基于文献快照的结构化辩论能提升耦合工程约束下的假说生成能力,并提供可复用的文本密集型科学发现工作流。

原文摘要 · Abstract (English)

Modern scientific discovery is bottlenecked not by data scarcity, but by the inability to synthesize fragmented knowledge into actionable hypotheses. This challenge is especially acute in battery materials research, where electrochemical performance, interfacial behavior, and manufacturing feasibility must be optimized simultaneously. Here, we present the Multi-Persona Debate System (MPDS), a literature-grounded framework for automated scientific hypothesis generation that combines literature retrieval, long-context large language model reasoning, corpus-driven persona induction, and structured multi-agent debate. MPDS constructs literature snapshots of up to 500 papers, grounds agents in role-specific evidence pools, and conducts a three-round citation-aware debate followed by moderator synthesis, enabling negotiation between personas while preserving evidence traceability. We evaluate MPDS using a temporally controlled protocol excluding direct access to target papers, including two held-out battery-materials case studies and a blinded comparison across 30 matched cases. In sodium-ion anode and all-solid-state battery cathode design tasks, MPDS recovered design logics aligned with experimentally validated solution spaces and generated more mechanistically explicit, process-aware proposals than simpler baselines. To assess the impact of personas and debate, we introduce Integrative Hypothesis Quality scoring. In ablation studies, MPDS achieved the highest mean score among five conditions, with its largest advantage in cross-perspective integration. A laboratory follow-up suggests utility as a diagnostic aid for identifying practical bottlenecks in workflows. These results indicate that structured debate over literature snapshots improves hypothesis formation under coupled engineering constraints and provides a reusable workflow for text-intensive scientific discovery.

科学发现多智能体假说生成电池材料

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