让超声影像学会识别解剖结构,提升医学图像表示学习的临床意义。
Anatomy-Anchored Self-Supervision: Distilling Vision Foundation Models for Invariant Ultrasound Representation

- 用可学习的提示机制实现无标注解剖分割,规模化处理超声图像。
- 在六个数据集上超越现有方法,保持临床部署所需的计算效率。
- 适合需要精准解剖对齐的医学影像模型研究者使用。
自监督预训练在医学影像中日益重要,但现有超声(US)图像方法多基于图像或帧级别,忽略解剖上下文,难以实现临床对齐的表征学习。本文提出解剖锚定自监督框架 ANAUS,将表征学习从通用视觉区域转向具有临床意义的解剖结构。通过可学习的潜在提示引擎与一次性的域适应,使 LP-SAM 模块实现大规模无标注解剖边界划分。在此解剖基础上,设计双策略自监督学习:跨视图语义感知的解剖分离对齐,强化相同解剖区域特征不变性并区分不同结构;以及上下文核心区域预测,迫使模型重建受损区域以捕捉细微结构细节。在六个公开数据集上的广泛评估显示,ANAUS 均显著优于当前最优方法,同时保持临床部署所需的计算效率。代码已开源。
原文摘要 · Abstract (English)
Self-supervised pre-training paradigm has gained increasing prominence for learning transferable representations in medical imaging, yet existing methods for ultrasound (US) images operate at the image or frame level, overlooking the anatomical context for clinical-aligned representation learning. In this work, we propose an anatomy-anchored ultrasound self-supervision framework ANAUS that shifts representation learning from generic visual regions to clinically meaningful anatomical structures. Utilizing a learnable latent prompt engine alongside a one-time domain adaptation on existing public image-mask pairs, we empower the LP-SAM module to achieve annotation-free anatomy delineation at scale. Building upon this anatomical grounding, we propose a dual-policy self-supervised learning paradigm consisting of inter-view semantics-aware anatomy-separating alignment and contextual core-region prediction to enhance representation learning. Specifically, the former enforces feature invariance within identical anatomical regions while promoting discriminability across distinct structures; the latter compels the model to reconstruct corrupted regions, thereby capturing fine-grained structural details. Extensive evaluations on six public datasets demonstrate that ANAUS consistently outstrips current state-of-the-art methods while maintaining the computational efficiency essential for clinical deployment. Code is available at https://github.com/zhcz328/ANAUS.
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