用热成像分析甲状腺结节,助力早期癌症筛查
An Approach for Thyroid Nodule Analysis Using Thermographic Images
- 提出热成像采集与自动配准协议,提升图像一致性
- 融合特征提取与图像处理,实现健康/异常患者分类
- 面向临床预防,适合内分泌科医生参考应用
甲状腺癌预计到2030年将成为女性第二、男性第三常见的癌症。早期检测显著提高生存率。热成像作为一种日益广泛应用的诊断工具,可用于检测甲状腺异常。本文综述热成像在甲状腺分析中的应用,提出图像采集规范与自动配准方法,并开展特征提取、图像处理及健康/非健康患者分类的初步分析。本研究为大学医院甲状腺肿瘤检测的试点项目,旨在支持内分泌科的预防性医疗行动。未来将提交至联邦弗洛里尼亚大学安东尼奥·佩德罗医院(HUAP-UFF)伦理与研究委员会及巴西卫生部伦理委员会审批,项目名称为:评估热成像在辅助诊断HUAP-UFF患者甲状腺结节中的重要性(Avaliação da importância da termografia no auxílio à investigação diagnóstica de nódulos tireoidianos em pacientes acompanhados no HUAP-UFF)。
原文摘要 · Abstract (English)
Thyroid cancer is said to be the second most common type of cancer in female individuals and the third in males by 2030, according to projections. In general, detecting cancer in its early stages improves the chance of survival of the individual. Thermography is a diagnostic tool that has been increasingly used to detect cancer and abnormalities, including that of thyroid. Various methods to segment and detect hot regions in thermograms and, consequently, to detect suspicious tissues present in these images have been proposed. It is well known that medical diagnosis yields a great deal of information. Thus, physicians have to comprehensively analyse and evaluate this information in a short period of time, which is infeasible in most cases. In this work, we perform a general review of thermography , focusing on the thyroid analysis. We propose protocols for image acquisiton and an autonomous registration for thyroid images. We also perform analyses of the image data, which include feature extraction, image processing, and a possible approach for classification of healthy or unhealthy patients. In summary, this work presents a pilot project for detection of tumors in our university hospital, which is part of an effort to support preventive medical actions in our endocrinology department. Under some future adjustments, this project will be submitted for approval by the ethics and research committee of Hospital Universitário Antonio Pedro at Universidade Federal Fluminense (HUAP-UFF) and to the Brazilian Ministry of Health Ethical committee under the name: Evaluation of the importance of thermography to aid diagnosis of thyroid nodules of patients in HUAP-UFF (in Portuguese: Avaliação da importância da termografia no auxílio à investigação diagnóstica de nódulos tireoidianos em pacientes acompanhados no HUAP-UFF).
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