用自监督变压器修复胎儿心率信号缺失,提升产前风险预测能力。
FHRFormer: A Self-Supervised Masked Transformer Framework for Fetal Heart Rate Time-Series Inpainting and Forecasting

- 基于掩码Transformer的自编码器,同时捕捉时序与频域特征。
- 在不同长度缺失数据下表现稳健,可实现信号修复与未来趋势预测。
- 适合用于研究数据回溯分析,也适用于可穿戴设备实时监测。
约10%新生儿出生时需帮助启动呼吸,约5%需通气支持。胎儿心率(FHR)监测在产前评估胎儿健康状况中至关重要,有助于识别异常模式并及时干预以降低分娩风险。利用人工智能分析大规模连续FHR监测数据,可能为预测新生儿呼吸支持需求提供新见解。近年来可穿戴式FHR监测仪的发展使孕妇在保持活动自由的同时实现持续监测。然而,母体移动或胎儿/母体体位变化常导致传感器移位,造成信号丢失,形成数据空白,限制了有效信息提取并阻碍自动化AI分析。传统方法如简单插值难以保留信号的频谱特性。本文提出一种基于掩码Transformer的自编码器方法,通过捕捉数据的局部时序与频域成分,重建缺失的FHR信号。该方法在不同缺失时长下均表现出鲁棒性,可用于信号补全与未来趋势预测。该方法可应用于历史研究数据,支持基于AI的风险算法开发;未来亦可集成至可穿戴设备,实现更早、更可靠的胎儿风险预警。
原文摘要 · Abstract (English)
Approximately 10% of newborns require assistance to initiate breathing at birth, and around 5% need ventilation support. Fetal heart rate (FHR) monitoring plays a crucial role in assessing fetal well-being during prenatal care, enabling the detection of abnormal patterns and supporting timely obstetric interventions to mitigate fetal risks during labor. Applying artificial intelligence (AI) methods to analyze large datasets of continuous FHR monitoring episodes with diverse outcomes may offer novel insights into predicting the risk of needing breathing assistance or interventions. Recent advances in wearable FHR monitors have enabled continuous fetal monitoring without compromising maternal mobility. However, sensor displacement during maternal movement, as well as changes in fetal or maternal position, often lead to signal dropout, resulting in gaps in recorded FHR data. Such missing data limits the extraction of meaningful insights and complicates automated (AI-based) analysis. Traditional approaches to handling missing data, such as simple interpolation techniques, often fail to preserve the spectral characteristics of the signals. In this paper, we propose a masked transformer-based autoencoder approach to reconstruct missing FHR signals by capturing both local temporal and frequency components of the data. The proposed method demonstrates robustness across varying durations of missing data and can be used for signal inpainting and forecasting. The proposed approach can be applied retrospectively to research datasets to support the development of AI-based risk algorithms. In the future, the proposed method could be integrated into wearable FHR monitoring devices to achieve earlier and more robust risk detection.
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