arXiv:2605.29731cs.LG2026-05

用可微分的4D高斯混合模型,从稀疏电极还原高密度脑电图。

EMAG: Differentiable 4D Gaussian Mixture Splatting for EEG Spatial Super-Resolution

论文配图:EMAG: Differentiable 4D Gaussian Mixture Splatting for EEG Spatial Super-Resolution
图 1 · 摘自论文原文
  • 将脑电源建模为各向异性4D高斯混合,参数化空间与时间耦合。
  • 在3个公开数据集上实现2x至16x超分辨率,性能优于现有方法。
  • 模型可直接可视化源分布,适合临床源定位与生物标志物研究。

高密度脑电图(HD-EEG)能精细测量皮层活动,但需昂贵设备和长时间设置,限制了其临床与科研应用。本文提出EMAG(EEG各向异性高斯混合),一种可微分框架,通过稀疏低密度(LD)电极重建HD-EEG信号。该方法将脑电来源表示为球形脑网格上多个各向异性4D空间-时间高斯混合,每个高斯由完整的4×4精度矩阵参数化,支持非对称空间扩散并显式耦合时空维度。前向模型通过可微高斯场贡献在电极位置生成头皮脑电图,实现端到端训练,无需显式源定位监督。在三个公开脑电基准数据集(Localize-MI、SEED、SEED-IV)上,以2x至8/16x超分辨率因子进行评估,EMAG在多数超分辨率倍数下优于当前最先进方法。显式的高斯参数化进一步支持对学习到的脑源配置进行直接可视化与可解释性分析,为源定位或生物标志物发现等临床与神经科学应用提供新路径。

原文摘要 · Abstract (English)

High-density electroencephalography (HD-EEG) enables fine-grained measurement of cortical activity but requires expensive hardware and lengthy setup times, limiting its clinical and research accessibility. We propose EMAG (EEG Mixture of Anisotropic Gaussians), a differentiable framework that reconstructs HD-EEG signals from a sparse subset of low-density (LD) electrodes by representing brain electrical sources as a mixture of anisotropic 4D space-time Gaussians. EMAG places a mixture of multiple Gaussians at each point of a spherical brain grid, each parameterized by a full 4 x 4 precision matrix, enabling anisotropic spatial spreads and explicit coupling between spatial and temporal dimensions. The forward model renders scalp EEG via differentiable Gaussian field contributions at electrode locations, enabling end-to-end training without explicit source localization supervision. We evaluate EMAG on three public EEG benchmarks (Localize-MI, SEED, and SEED-IV) at super-resolution factors of 2x through 8/16x. EMAG outperforms the current state-of-the-art EEG super-resolution method at most super-resolution factors on three standard benchmarks (Localize-MI, SEED, SEED-IV). The explicit Gaussian parameterization further enables direct visualization and interpretability of learned brain source configurations, potentially opening avenues for clinical and neuroscientific applications, such as source localization or biomarker discovery.

脑电图超分辨率可微分建模

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