用多网格分层学习加速大型飞机三维流场模拟，提升效率3至8倍。

High-fidelity computational fluid dynamics is essential for aerospace design, but engineering-scale simulations of practical three-dimensional aircraft remain computationally expensive. Learning-based flow-field initialization can improve efficiency by reducing the numerical distance between the initial and converged solutions, yet existing deep learning approaches remain difficult to scale to large three-dimensional aircraft flows with multiscale regional heterogeneity. Most prior studies therefore focus on two-dimensional problems, surface quantities, integral aerodynamic coefficients, or simplified three-dimensional cases with limited grid resolution.Here we propose MHLF, a multigrid-hierarchical learning framework for accelerating engineering-scale aircraft flow simulations while preserving high-fidelity numerical accuracy. MHLF combines a topologically consistent geometric multigrid representation with a hierarchical strategy that captures regional flow heterogeneity during both prediction and subsequent CFD correction. Across three engineering-scale aircraft cases spanning Mach 0.15 to 6.0 and covering subsonic, transonic and supersonic regimes, MHLF accelerates convergence without sacrificing flow-field accuracy, achieving a 3 to 8 times efficiency improvement over conventional initialization. These results demonstrate practical full-flow-field prediction for large three-dimensional aircraft within the CFD domain and provide a foundation for data-driven acceleration of high-fidelity aircraft flow simulation.