用随机图模型提升传染病预测精度,兼顾大中小区域网络。
Spatio-temporal stochastic graph-based learning for infectious disease forecasting

- 引入随机性与不确定性建模,统一处理不同规模地理网络。
- 在美3218县和匈20县数据上表现优于四种基线模型。
- 对高频微小波动不敏感,适合真实世界疫情长期趋势预测。
基于时空图的模型常用于预测新冠、水痘等传染病的新发病例,但其学习过程中的随机建模研究不足,且极少在大型国家全数据集上验证。本文提出一种融合随机形式化与不确定性近似的时空图架构,可统一编码大、小人口地理网络。基于美国新冠疫情与匈牙利水痘疫情两组真实数据,结果显示该方法在2022年美国首波疫情及2012–2014年匈牙利水痘波段预测中表现优异。与四种基线模型对比,该方法在所有3,218个美国县和20个匈牙利县的周度新发病例预测中均具竞争力。尽管存在一步延迟,仍能更好反映整体流行病进程,同时降低对高频率、低振幅波动的敏感性。
原文摘要 · Abstract (English)
Spatio-temporal graph-based models have typically been used to forecast new cases of infectious diseases such as COVID-19 and chickenpox outbreaks. However, the use of stochastic modelling into their learning process has been surprisingly under-investigated and rarely considered entire data sets of large countries. As a result, it is unknown whether these models would provide accurate forecasts in real-world disease spread scenarios. In this work, we propose a spatio-temporal stochastic graph-based architecture that integrates a stochastic formulation and uncertainty approximation process to forecast new infectious disease cases. We find that our approach can adapt to encode large and small population geographical networks within a single model architecture. Using two real-world data sets, COVID-19 in the US and chickenpox in Hungary, we report an enhanced effect of the proposed architecture across predictions of the 2022 first wave for COVID-19 in the US and comparative results of chickenpox waves during 2012-2014 in Hungary. By benchmarking with four spatio-temporal graph-based models, quantitative results show competitive overall weekly performance of the proposed approach on forecasting new cases for all 3,218 US counties and all 20 Hungary counties. The proposed approach can represent overall epidemic progression relative to baselines, though with a one-step delay; while exhibiting a reduced sensitivity to high-frequency and low-amplitude variability.
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