提出EMTrack框架,实现视网膜血流中红细胞的自动检测与追踪。
Automated Erythrocyte Detection and Tracking for Retinal Blood Flow Quantification in Erythrocyte-Mediated Angiography

- 引入流动上下文模块区分运动与静止红细胞
- 在RBF-EMA数据集上检测与追踪准确率显著提升
- 适用于眼科疾病血流自动化量化研究
毛细血管水平视网膜血流(RBF)在多种眼病中具有重要生物标志物潜力,但现有测量手段有限。新兴的红细胞介导血管造影(EMA)技术通过可视化单个红细胞实现毛细血管水平血流测量,但其自动化红细胞检测与追踪仍处于探索阶段。为此,本文提出EMTrack框架,包含用于区分运动与静止红细胞的流动上下文模块,以及具备拓扑感知能力的追踪策略,可应对大帧间位移和剧烈运动变化。同时,构建了RBF-EMA数据集,包含完整的红细胞检测与追踪标注。实验表明,该方法在检测与追踪任务上的定量与定性表现均优于基线模型,且血流量化结果验证了其在自动化视网膜血流测量中的巨大潜力。
原文摘要 · Abstract (English)
Capillary-level retinal blood flow (RBF) has strong potential as a biomarker for various ocular diseases. However, modalities for measuring capillary-level RBF remain limited. Erythrocyte-mediated angiography (EMA), an emerging imaging technique, enables capillary-level RBF measurement by visualizing individual erythrocytes, yet automated erythrocyte detection and tracking, which are essential for quantifying blood flow, remain largely unexplored. To address this gap, we propose EMTrack, a novel framework featuring a flow-context module for erythrocyte detection that distinguishes moving from paused cells and a topology-aware tracking strategy that enables tracking under large inter-frame displacements and substantial motion variations. In addition, we establish RBF-EMA, a new EMA dataset with comprehensive erythrocyte detection and tracking annotations. Experimental results demonstrate that our method outperforms baseline methods both quantitatively and qualitatively on detection and tracking tasks in the RBF-EMA dataset. Moreover, RBF quantification results highlight the strong potential of our framework for automated retinal blood flow measurement.
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