研究发现不同族裔儿童自闭症风险差异显著，白人风险高，中东族裔风险低。
Analysis of Ethnic Disparities in Autism Spectrum Disorder among Toddlers
- 比较三族裔自闭症特征与行为评分，用逻辑回归分析族裔影响。
- 白人儿童自闭症风险比亚裔高81%，中东族裔则低79%。
- 结果提示需在诊断中考虑族裔差异，尤其对男童和黄疸新生儿。
自闭症谱系障碍（ASD）是一种以沟通与行为挑战为特征的神经发育障碍。本研究考察了族裔（白人欧洲裔、亚裔、中东裔）与自闭症特征、行为评分、性别及新生儿黄疸之间的关系。通过逻辑回归分析显示，族裔对自闭症发病率有显著影响：相较于亚裔，白人欧洲裔儿童自闭症风险高出81%，中东裔儿童风险则降低79%。同时验证了先前研究结论，即新生儿黄疸是自闭症的重要预测因子，男性儿童患自闭症的风险远高于女性儿童。结果表明，应建立考虑族裔差异的诊断框架与干预策略，以更准确评估自闭症特征。
原文摘要 · Abstract (English)
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by challenges in communication and behavior. This study examines the relationship between ethnicity and ASD traits, along with behavioural scores, sex and neonatal jaundice across three ethnic groups: White Europeans, Asians, and Middle Eastern individuals. We perform a logistic regression and show that ethnicity has a significant effect on incidence of ASD. White Europeans are 81% increased risk of ASD and Middle Easterners are at 79\% reduced risk of ASD compared to Asians. We also confirm earlier studied which show that neonatal jaundice is a significant predictor of ASD, while male children are at much higher risk of ASD compared to female children. These results suggest the need for diagnostic frameworks and interventions that account for ethnic in the presentation and assessment of ASD traits
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