arXiv:2606.02403cs.CLcs.AI2026-06ACL

AutoForest自动从论文生成可发表的森林图,省去人工提取和计算。

AutoForest: Automatically Generating Forest Plots from Biomedical Studies with End-to-End Evidence Extraction and Synthesis

论文配图:AutoForest: Automatically Generating Forest Plots from Biomedical Studies with End-to-End Evidence Extraction and Synthesis
图 1 · 摘自论文原文
  • 端到端提取研究文本中的干预、对照和结局信息
  • 自动完成数据提取与统计合并,生成标准化森林图
  • 适合临床医生快速做系统评价,降低元分析门槛

系统评价依赖森林图整合生物医学研究的定量证据,但生成过程碎片化且耗时。研究人员需解读复杂临床文本,手动提取试验结果,定义干预与对照,统一不一致的研究设计,并进行元分析计算——通常需使用专业软件并提供结构化输入,要求领域知识。尽管近期工作表明大语言模型可从非结构化文本中提取研究级数据,但尚无系统能实现从原始文档到合成森林图的全流程自动化。为此,我们提出AutoForest,首个端到端系统,可直接从生物医学论文生成可发表的森林图。给定一篇或多篇研究论文,AutoForest自动建议ICO(干预、对照、结局)元素,提取结局数据,执行统计合成,并渲染最终森林图。我们描述了系统架构与用户界面,并通过涉及临床医生的用户研究,展示了其在真实案例中的有效性,证明该系统可加速证据整合,显著降低开展元分析的门槛。

原文摘要 · Abstract (English)

Systematic reviews rely on forest plots to synthesise quantitative evidence across biomedical studies, but generating them remains a fragmented and labour-intensive process. Researchers must interpret complex clinical texts, manually extract outcome data from trials, define appropriate interventions and comparators, harmonise inconsistent study designs, and carry out meta-analytic computations-typically using specialised software that demands structured inputs and domain expertise. While recent work has demonstrated that large language models can extract study-level data from unstructured text, no existing system automates the complete pipeline from raw documents to synthesised forest plots. To address this gap, we introduce AutoForest, the first end-to-end system that generates publication-ready forest plots directly from biomedical papers. Given one or more study papers, AutoForest automatically suggests ICO (Intervention, Comparator, Outcome) elements, extracts outcome data, performs statistical synthesis, and renders the final forest plot. We describe the system architecture, user interface and demonstrate its effectiveness on real-world examples through a user study involving clinicians, showing how AutoForest can accelerate evidence synthesis and substantially lower the barrier to conducting meta-analyses.

证据整合自然语言处理自动化元分析

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