arXiv:2606.02639eess.IVcs.AI2026-06

用三投影重建肺结节体积,精度接近放射科医生共识。

Sparse-View Lung Nodule Volumetry from Digitally Reconstructed Radiographs via AReT: Anatomy-Regularized TensoRF

论文配图:Sparse-View Lung Nodule Volumetry from Digitally Reconstructed Radiographs via AReT: Anatomy-Regularized TensoRF
图 1 · 摘自论文原文
  • 修正TensoRF密度偏移问题,恢复梯度流以支持稀疏视角重建。
  • 在LIDC-IDRI数据集上实现14个≥10mm结节的体积相关性r=0.983。
  • 结合解剖先验正则化,比生成模型引导方法更优,适合临床小样本应用。

我们发现将TensoRF用于X射线衰减场时存在此前未报告的失效模式:默认的密度偏移-10(原为RGB场景重建设计)会抑制密度梯度,导致无论学习率或正则化策略如何,稀疏视角医学重建均失败。将密度偏移设为零后,梯度得以恢复,仅需三个正交投影即可实现肺结节稳定体积分层重建。基于此,我们提出AReT——一种结合解剖先验正则化的张量辐射场框架,利用来自LIDC-IDRI数据集(19名患者,放射科医生标注结节)的冠状、矢状和轴向投影进行肺结节重建。不同于需要密集多视角采集的现有NeRF方法,AReT专为稀疏胸腔成像设计,引入结合L1稀疏性与总变差平滑性的解剖感知正则化。11种重建策略的系统对比显示,解剖感知正则化始终优于生成先验引导方法。与放射科医生共识分割相比,AReT在≥10 mm的可行动结节(n=14)上达到皮尔逊相关系数r=0.983(p<0.0001),中位绝对体积误差11.4%,系统偏差近零(-77.3 mm³),较球形体积近似提升8.4倍。

原文摘要 · Abstract (English)

We identify and resolve a previously unreported failure mode in TensoRF when applied to X-ray attenuation fields: the default density shift of -10, originally introduced for RGB scene reconstruction, suppresses density gradients and prevents sparse-view medical reconstruction regardless of learning rate or regularization strategy. Setting the density shift to zero restores gradient flow and enables stable volumetric reconstruction of pulmonary nodules from only three orthogonal X-ray projections. Building on this, we propose AReT, an anatomy-regularized tensorial radiance field framework for lung nodule reconstruction using coronal, sagittal, and axial projections from the LIDC-IDRI dataset (19 patients, radiologist-annotated nodules). Unlike existing NeRF approaches requiring dense multi-view acquisition, AReT is designed for sparse-view thoracic imaging and incorporates chest-anatomy-aware regularization combining L1 sparsity and total variation smoothness. A systematic comparison across 11 reconstruction strategies shows anatomy-aware regularization consistently outperforms generative-prior-guided approaches. Evaluated against radiologist consensus segmentations, AReT achieves Pearson r=0.983 (p<0.0001) for clinically actionable nodules >=10 mm (n=14), median absolute volumetric error of 11.4%, near-zero systematic bias of -77.3 mm^3, and 8.4x improvement over spherical volume approximation.

肺结节稀疏视角张量辐射场解剖正则

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