arXiv:2606.04419eess.IVcs.AI2026-06中稿 · MICCAI 2026

利用患者历史影像提升快速MRI重建质量,避免配准与协议差异干扰。

L-TGVN: Leveraging Longitudinal Priors for Personalized Rapid MRI

  • 基于纵向先验的可信赖变分网络,直接融合历史扫描信息。
  • 在4倍加速下仍保持细微结构清晰,定量指标优于基线方法。
  • 无需配准或协议对齐,适合临床随访场景快速重建。

MRI具有优异的软组织对比度且无电离辐射,但长扫描时间会增加患者不适,提高检查成本并降低扫描仪吞吐量。缩短扫描时间的常见方法是减少采样量,但这导致病态线性逆问题;恢复诊断级图像需引入超出测量数据的先验知识。在随访检查中,患者最近一次的扫描可提供高度相关的个体化上下文,但实际应用受限于时间变化(如病灶进展)、扫描间错位以及不同采集协议间的漂移。本文提出L-TGVN——一种纵向可信引导的变分网络,利用先验扫描作为辅助信息,从严重欠采样的测量中重建当前扫描。关键在于,该方法限制先验扫描的影响必须与实际测量一致。不同于多数现有纵向重建方法,L-TGVN无需显式预配准先验与当前扫描,亦能处理不同访问间的采集协议差异。我们在匹配容量的基线模型上评估了L-TGVN,包括依赖先验和不使用先验的方法,在标准定量指标上均取得一致提升,并在高加速条件下更好保留精细结构。源代码已公开于github.com/sodicksonlab/L-TGVN。

原文摘要 · Abstract (English)

MRI provides excellent soft-tissue contrast without ionizing radiation, but long acquisition times increase patient discomfort while also raising exam costs and limiting scanner throughput. A common approach to reduce scan time is to acquire fewer measurements, which yields an ill-posed linear inverse problem; recovering diagnostic-quality images therefore requires incorporating prior knowledge beyond the measured data. In follow-up exams, the most recent prior scan of a patient can provide a highly informative subject-specific context, but practical use is complicated by temporal changes (including pathology progression), misalignment between scans, and protocol drift across acquisitions. In this work, we introduce L-TGVN, a Longitudinal Trust-Guided Variational Network that leverages prior scans as side information to reconstruct the current scan from heavily undersampled measurements. Crucially, L-TGVN constrains the influence of prior scans to be consistent with the acquired measurements. Unlike many existing longitudinal reconstruction methods, it does not require explicit pre-registration between prior and current scans. It further accommodates differences in acquisition protocols across visits (e.g., changes in sequence parameters). We evaluate L-TGVN against matched-capacity baselines, including prior-guided methods and methods that do not use longitudinal priors, and observe consistent improvements in standard quantitative metrics together with better preservation of fine structures at challenging accelerations. Source code is available at github.com/sodicksonlab/L-TGVN.

快速MRI纵向重建先验引导医学图像

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