arXiv:2606.06718cs.LGcs.AI2026-06

提出多尺度注意力与不平衡感知对比学习模型,提升心电图异常检测精度与可解释性。

MSAIC-Net: A Multi-Scale Attention and Imbalance-Aware Contrastive Network for ECG-Based Myocardial Substrate Abnormality Detection

论文配图:MSAIC-Net: A Multi-Scale Attention and Imbalance-Aware Contrastive Network for ECG-Based Myocardial Substrate Abnormality Detection
图 1 · 摘自论文原文
  • 多尺度空洞卷积捕获不同时间跨度的心电信号特征
  • 不平衡感知对比学习使正常与异常样本区分更清晰,准确率显著提升
  • 通过导联重要性分析增强模型可解释性,适合临床辅助诊断场景

心肌基质异常(如心肌瘢痕和心肌梗死)与不良心血管结局相关。心电图(ECG)是低成本、广泛可用的检测工具,但受限于导联依赖性表现多样、多导联高维信号、类别不平衡及深度学习模型可解释性差等问题,基于ECG的检测仍具挑战。本文提出多尺度注意力增强卷积网络(MSAIC-Net),采用并行空洞卷积分支提取多时域感受野特征,捕捉局部与长程时间模式;通过通道注意力自适应重加权导联与特征通道表示;引入新型不平衡感知监督对比学习策略,促使同类别样本形成紧凑聚类,同时增强正常与异常样本间的分离度;进一步结合导联级置换重要性分析,量化各导联贡献,提升模型可解释性。在两个互补数据集上验证:来自弗吉尼亚大学(UVA)健康系统的低数据量机构队列用于心肌瘢痕分类,以及来自PhysioNet的大规模公开PTB-XL数据集用于心肌梗死识别。实验表明,MSAIC-Net优于基线模型,尤其在低数据量的UVA队列中表现突出。整体框架为心电图心肌基质异常检测提供了有效且可解释的解决方案。

原文摘要 · Abstract (English)

Myocardial substrate abnormalities, such as myocardial scar and myocardial infarction (MI), are associated with adverse cardiovascular outcomes. Electrocardiography (ECG) provides a low-cost and widely available tool for detecting these abnormalities, but ECG-based detection remains challenging due to heterogeneous lead-dependent manifestations, high-dimensional multi-lead signals, class imbalance, and the limited interpretability of deep learning models. We propose a multi-scale attention-enhanced convolutional network (MSAIC-Net) for ECG-based myocardial substrate abnormality detection. MSAIC-Net employs parallel atrous convolutional branches to extract ECG features across multiple temporal receptive fields. %, enabling the model to capture both local and longer-range temporal patterns. Channel attention is then used to adaptively reweight informative lead-wise and feature-channel representations. To address class imbalance and improve feature separability, we introduce a novel imbalance-aware supervised contrastive learning strategy that encourages samples from the same class to form compact representations while increasing separation between abnormal and normal samples. Lead-wise permutation importance is further incorporated to quantify the contribution of each ECG lead and improve model interpretability. The proposed method was evaluated on two complementary datasets: a low-data institutional cohort from the University of Virginia (UVA) Health System for myocardial scar classification and the large-scale public PTB-XL dataset from PhysioNet for MI identification. Experimental results show that MSAIC-Net outperforms baseline models, with particularly pronounced improvements in the low-data UVA cohort. Overall, the proposed framework provides an effective and interpretable approach for ECG-based detection of myocardial substrate abnormalities.

心电图分析异常检测对比学习可解释性

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