首个可精准分割全尺寸血管的CT图像模型,助力心血管系统整体分析。
vesselFM-CT: Segmenting All Blood Vessels in CT Images for System-Level Cardiovascular Analysis

- 基于迭代训练与新型管状损失函数,统一处理不同粗细血管。
- 在3D CT图像中实现从大动脉到微小肠系膜血管的完整分割。
- 适用于疾病自动分类与合成影像生成,推动临床与生理研究。
人体血管网络具有半径、长度、拓扑结构和分支模式的剧烈变化,加之解剖背景的位置差异,给心血管系统的鲁棒性、大规模分析带来巨大挑战。现有研究多聚焦于孤立的局部血管段,难以评估血管系统的整体健康与功能完整性。本文提出在CT图像中分割全部血管的任务,并引入vesselFM-CT——首个能稳健分割3D CT图像中所有血管(从主干血管至微小肠系膜血管)的模型。该模型通过迭代多步训练,优化自研的TubeLoss损失函数,有效应对血管系统的内在异质性。实验表明,vesselFM-CT优于所有基线方法,实现了从CT图像中自动化、高精度提取心血管系统,为疾病自动分类、合成CT图像生成等应用打开新路径。
原文摘要 · Abstract (English)
The vascular network in the human body is characterized by blood vessels exhibiting drastic structural variations in radius, length, topological properties, and branching patterns. This heterogeneity, together with location-specific anatomical background variations, poses a significant challenge for robust, large-scale analysis of the entire cardiovascular system. As a result, most research has focused on narrow, isolated segments of the vascular network. While such targeted studies provide valuable insights, they inherently limit the ability to assess the systemic health and functional integrity of the vascular network as a whole. In this work, we aim to bridge this gap to advance both clinical diagnostics and our fundamental understanding of vascular physiology. We propose the task of segmenting all vessels in CT images, ranging from the largest components of the cardiovascular system to even minuscule mesenteric vessels. To this end, we introduce vesselFM-CT, the first model capable of robustly segmenting all blood vessels in 3D CT images. VesselFM-CT is trained via an iterative, multi-step process and optimizes our proposed TubeLoss loss function, effectively addressing the inherent heterogeneity of the cardiovascular system. We demonstrate that vesselFM-CT outperforms all baselines and enables automated, precise extraction of the cardiovascular system from CT images, thereby unlocking a wide range of clinical and technical perspectives, including automated disease classification and synthetic CT image generation.
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