用动态增强提升心电检测模型在真实场景的可靠性
A Comprehensive Inference-Time Augmentation Framework in Physiological Signals: Application to PPG-Based AF Detection
- 推理时动态应用13种信号增强方法,参数通过贝叶斯优化
- 最高使AF识别准确率提升8.5%(GPT-PPG),误报率降4.4%
- 适合无法重训练的临床部署场景,可推广至其他生理信号
真实场景中生理信号分类受传感器噪声、运动伪影及数据分布偏移挑战。推理时增强(ITA)在不重新训练的前提下,通过推理阶段应用数据增强提升模型鲁棒性。现有研究在生理信号上应用有限,仅使用少量固定参数的增强方法。本文提出统一的ITA框架,融合时域、幅值域、频域及伪影注入共13种变换,并通过贝叶斯优化调节超参数。在五个数据集(超400名患者,约9800小时记录)上,基于30秒脉搏波信号(PPG)进行房颤(AF)检测,测试GPT-PPG与ResNet模型。结果表明,标准ITA使AUROC最高提升8.5%(GPT-PPG)和0.7%(ResNet),AUPRC最高提升10.6%(GPT-PPG)和0.8%(ResNet)。选择性ITA进一步将非房颤数据集平均假阳性率降低4.4%(GPT-PPG)和1.3%(ResNet)。该研究验证了ITA作为无需重训练的实用方案,在实际部署中显著提升PPG房颤检测可靠性,具广泛适用性。
原文摘要 · Abstract (English)
Objective: Accurate classification of physiological signals in real-world deployments is challenged by sensor noise, motion artifacts, and distribution shifts between training and deployment data. Inference-time augmentation (ITA), which applies augmentations during inference rather than retraining, offers a simple, model-agnostic mechanism to improve robustness. However, ITA application to physiological signals has remained narrow in scope, relying on limited augmentation methods with fixed, unoptimized parameters. This work proposes a unified ITA framework to address that gap. Approach: The framework incorporates 13 augmentation methods spanning time-domain, amplitude-domain, frequency-domain, and artifact-injection transformations, with hyperparameters optimized via Bayesian optimization. We evaluate on atrial fibrillation (AF) detection from 30-second PPG signals using GPT-PPG and ResNet across five datasets comprising more than 400 patients and ${\sim}$9,800 hours of recording. Main results: Standard ITA consistently improved AUROC (up to 8.5% for GPT-PPG and 0.7% for ResNet) and AUPRC (up to 10.6% for GPT-PPG and 0.8% for ResNet). Selective ITA further reduced average FPR by up to 4.4% (GPT-PPG) and 1.3% (ResNet) on non-AF datasets. Significance: These findings establish ITA as a practical, model-agnostic approach for improving PPG-based AF classification reliability in deployment settings where retraining is not feasible, with broader applicability to physiological signal analysis.
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