arXiv:2606.10756cs.CVphysics.med-ph2026-06

用动态驱动的隐式表示,加速脑功能MRI重建并提升信号检测能力

DD-INR: Dynamics-Driven Implicit Neural Representation for Accelerated Whole-Brain Functional MRI Reconstruction

论文配图:DD-INR: Dynamics-Driven Implicit Neural Representation for Accelerated Whole-Brain Functional MRI Reconstruction
图 1 · 摘自论文原文
  • 分离静态背景与动态变化,仅用隐式网络建模激活部分
  • 在模拟和真实数据上均优于传统方法,提升图像质量和激活模式还原
  • 适合需要快速扫描且关注微弱神经信号的研究者

加速采集可提升脑部神经血管(BOLD)活动的检测能力,但高k空间欠采样使图像重建困难:任务诱发的BOLD信号幅度小,传统解剖成像重建方法因侧重空间精度而难以恢复,忽略时间保真度。我们提出DD-INR,一种面向加速fMRI的动力学驱动隐式神经表示框架,利用非相干的时间变化采样与定制的时空先验,在仿真和在体实验中均优于传统方法,提升了图像质量与激活模式还原能力。该方法将fMRI数据分解为静态背景与时间变化的动态成分,仅用专用隐式神经网络(INR)表示动态部分,使模型容量集中于激活相关变化,同时保持紧凑。总体而言,DD-INR为加速fMRI重建提供了有效框架,有望在实际扫描时间内增强fMRI研究的敏感性与鲁棒性。源代码已公开于https://github.com/JoosenLi/DD-INR。

原文摘要 · Abstract (English)

Accelerated acquisition of fMRI enables enhanced detection of neurovascular (BOLD) activity in the brain, but image reconstruction becomes challenging with high k-space undersampling: Task-evoked BOLD signals are small in magnitude, which traditional anatomical MRI reconstruction methods fail to recover, as they favor spatial accuracy over temporal fidelity. We present DD-INR, a Dynamics-Driven Implicit Neural Representation framework tailored for accelerated fMRI that benefits from incoherent time-varying sampling and a tailored spatiotemporal prior, outperforming traditional methods, demonstrated in simulation and in-vivo acquisition, both in terms of image quality and retrieval of activation patterns. DD-INR achieves this by splitting the fMRI data into a static background and a temporally varying dynamic component, representing only the dynamics with a dedicated INR, thereby focusing the model's capacity on activation-relevant changes while remaining compact. In general, DD-INR provides a promising framework for accelerated fMRI reconstruction, with the potential to improve the sensitivity and robustness of fMRI studies within practical scan time limits. The source code is available at https://github.com/JoosenLi/DD-INR.

功能MRI隐式表示加速重建

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