让AI医生像真人一样从诊疗经验中持续进化,自动优化诊断与治疗方案。
Toward Vibe Medicine: A Self-Evolving Multi-Agent Framework for Clinical Decision Support

- 构建三类智能体协同工作,通过反馈循环实现自我演化。
- 在复杂临床场景中显著提升决策质量,尤其擅长长期治疗规划。
- 适合医疗AI研发者与临床决策系统设计者参考,推动精准医疗发展。
近年来,大语言模型与自主智能体的发展推动了医疗领域的变革,提升了诊断效率和治疗效果。然而,现有AI系统多依赖预训练知识与固定流程,难以从包含患者结局与过往失败的交互历史中动态学习。为此,我们提出VIBEMed,一种具备自演化机制与架构级安全沙箱的多智能体框架,用于增强临床决策支持。该系统集成三种专业智能体:临床诊断智能体(CDA)负责生成诊断假设,治疗执行智能体(TEA)制定治疗方案,临床演化管理智能体(CEMA)将长期临床反馈提炼为可复用的知识,实现多模态患者信息到个性化医疗决策的转化。通过自演化机制,系统可在记忆、模型行为与决策策略层面进行迭代更新,实现持续改进。实验表明,VIBEMed在需要综合判断与长期规划的复杂病例中表现优异,尤其在肿瘤治疗规划等挑战性任务中展现出可靠的端到端决策能力,验证了其在真实临床环境中的可行性。总体而言,VIBEMed为突破静态AI系统局限提供了可行路径,展示了多智能体协作与持续演化的结合对推进精准医学的重要价值。
原文摘要 · Abstract (English)
In recent years, the advances of large language models and autonomous agents have revolutionized the healthcare field, facilitating diagnosis and improving treatment results. However, most existing AI systems rely on pre-trained knowledge and predefined pipelines, which struggle to learn dynamically from the interactive chat session history that contains patient outcomes and past failures. To address this limitation, we propose VIBEMed, a multi-agent framework with a built-in self-evolution mechanism and architecture-level safety sandbox for robust clinical decision support. The system integrates three specialized agents, including a Clinical Diagnostic Agent (CDA) for hypothesis generation, a Therapeutic Execution Agent (TEA) for treatment planning, and a Clinical Evolution Manager Agent (CEMA) that distills longitudinal clinical feedback into reusable knowledge, transforming multimodal patient information into personalized medical decisions. Through self-evolution mechanism, the framework enables iterative updates across memory, model behavior, and decision strategies, allowing the system to improve over time. Experimental results show that VIBEMed demonstrates superior performance through its evolving mechanism in complex clinical cases, particularly in tasks that require integrated decision-making and longitudinal planning. The framework also supports reliable end-to-end decisions in challenging scenarios such as oncology treatment planning, highlighting its feasibility in real-world clinical contexts. Overall, VIBEMed provides a practical path beyond static AI systems toward adaptive, experience-driven clinical decision support, demonstrating the value of combining multi-agent collaboration with continuous evolution for advancing precision medicine.
Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。