arXiv:2606.15976cs.CV2026-06中稿 · the 29th Internati…

用统一几何先验提升医学图像分割的通用性与精度。

HadBalance: A Plug-and-Play Unified Global Geometric Prior Framework for Generalizable Biomedical Segmentation

论文配图:HadBalance: A Plug-and-Play Unified Global Geometric Prior Framework for Generalizable Biomedical Segmentation
图 1 · 摘自论文原文
  • 基于近凸形状特性设计可迁移的全局几何正则化方法。
  • 自适应平衡先验与分割目标,避免过度平滑真实凹陷结构。
  • 适用于多种器官和成像模态,兼容性强且无需重新训练。

精准的医学图像分割对临床诊断至关重要。几何线索(如边界、形状、拓扑)可增强结构一致性,但现有方法多为特定任务设计,缺乏跨器官与模态的统一几何基础。我们观察到,许多医学分割目标可近似为全局近凸形状——即任意两点间连线仍位于区域内,尽管存在局部凹陷或边界不规则。基于此,我们从Hadwiger定理推导出由面积A、周长P和欧拉示性数χ构成的可解释全局正则化项,实现跨器官与模态的迁移。然而,因医学数据形状异质性强,统一施加近凸先验可能过度正则化具有显著凹陷的解剖结构,导致凹陷与细节丢失,降低分割精度。为此,我们提出冲突感知目标平衡(CAOB),以梯度感知方式将形状先验与分割联合优化:对每个先验,仅移除与分割梯度冲突的部分,保留一致成分,并动态调节目标影响权重,防止先验主导。该方法使形状先验在异质数据上稳定使用,同时保留真实凹陷与精细结构。我们将其命名为Plug-and-Play框架HadBalance。

原文摘要 · Abstract (English)

Precise biomedical image segmentation is crucial for clinical diagnosis. Geometric cues (e.g., boundary, shape, and topology) can improve structural consistency, yet most are task-specific and lack a unified geometric foundation that generalizes across organs and modalities. We are motivated by the observation that several medical segmentation targets can be approximated as globally near-convex shapes. A convex region is one in which any two interior points can be connected by a line segment entirely contained within the region. In practice, medical targets may exhibit small local concavities or boundary irregularities; we refer to such globally convex-like shapes as near-convex. Motivated by this, we derive Hadwiger Shape Priors from Hadwiger's theorem as an interpretable global regularizer using three 2D measures: area A, perimeter P, and Euler characteristic chi, enabling transfer across organs and modalities. However, because medical datasets are shape-heterogeneous, enforcing near-convex priors uniformly can over-regularize non-convex anatomy with significant concavities, washing out concavities and fine details and degrading segmentation accuracy. To address this challenge, we propose Conflict-Aware Objective Balancing (CAOB), which integrates shape priors with segmentation in a gradient-aware manner. For each prior, CAOB removes only the gradient component that conflicts with segmentation while preserving the remaining aligned component, and adaptively regulates objective influences to prevent prior dominance. This enables stable use of shape priors on shape-heterogeneous data without erasing genuine concavities or fine structural details. We call this plug-and-play framework HadBalance.

医学分割几何先验泛化能力形状约束

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