用无造影CT生成类似增强CT的诊断结果,降低风险与负担
A Multi-Center Benchmark for Abdominal Disease Diagnosis and Report Generation from Non-Contrast CT

- 从单期无造影CT学习生成增强影像特征
- 内部与外部数据集上平均多器官AUC分别达69.1%和63.1%
- 适合关注安全影像流程与自动化报告的研究者
多期增强CT(CECT)广泛用于腹部病灶分析,但存在造影剂肾病风险,增加扫描负担,并加重放射科医生工作量。为应对这些挑战,我们提出一个跨中心的多器官腹部疾病诊断与自动化报告生成基准,通过单期非增强CT(NCCT)学习生成增强影像特征。为此,我们从两个中心收集了配对的NCCT-CECT影像及其对应增强报告,划分为内部训练集与外部验证队列。在统一评估协议下,我们测试了五种主流深度学习模型,涵盖胸腔特化、腹部特化及通用多模态架构。实验表明,NCCT仍保留有效诊断信息,在内部队列上平均多器官AUC为69.1%,外部队列上为63.1%。通过公开数据集与标准化基准,本研究旨在推动更安全、高效、全球可及的无造影腹部成像流程发展。代码已开源:https://github.com/xmed-lab/TriALS-Report。
原文摘要 · Abstract (English)
Multiphasic contrast-enhanced CT (CECT) is widely used for abdominal lesion characterization, yet it carries inherent risks of contrast-induced nephropathy, escalates acquisition burden, and heavily contributes to radiologist workload. To address these challenges, we introduce a novel multi-center benchmark for multi-organ abdominal disease diagnosis and automated radiology report generation, which learns to synthesize contrast-enhanced findings from single-phase non-contrast CT (NCCT). To support this, we curated a large-scale dataset of paired NCCT-CECT studies and their corresponding contrast-enhanced radiology reports from two centers, partitioned into internal sets and an external validation cohort. Under a unified evaluation protocol, we benchmarked five contemporary deep learning architectures encompassing chest-specific, abdomen-specific, and general-purpose multimodal domains. Extensive experiments demonstrate that NCCT retains diagnostic signals, achieving an average multi-organ AUC of 69.1% on the internal cohort and 63.1% on the external cohort, respectively. By releasing this dataset and standardized benchmark publicly, this study aims to catalyze future research into safer, resource-efficient, and globally accessible contrast-free abdominal imaging workflows. Code is available at: https://github.com/xmed-lab/TriALS-Report.
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